KRAS-targeted therapies in advanced solid cancers: drug the undruggable?

被引：5
|
作者：
Saleh, Khalil [1 ]
Kordahi, Manal [2 ]
Felefly, Tony [3 ]
Kourie, Hampig Raphael [4 ]
Khalife, Nadine [5 ]
机构：
[1] Gustave Roussy Canc Campus, Dept Hematol, F-94800 Villejuif, France
[2] Natl Inst Pathol, Dept Pathol, Baabda 1003, Lebanon
[3] St Joseph Univ, Sch Med, Dept Radiat Oncol, Hotel Dieu France Univ Hosp, Beirut 1100, Lebanon
[4] St Joseph Univ, Fac Med, Dept Hematol Oncol, Beirut 1100, Lebanon
[5] Gustave Roussy Canc Campus, Dept Med Oncol, F-94800 Villejuif, France
来源：
PHARMACOGENOMICS | 2021年 / 22卷 / 10期
关键词：
adagrasib; colorectal cancer; KRAS(G12C) mutations; non-small-cell lung cancer; RAS; sotorasib; KRYSTAL-1; ACTIVITY; ADAGRASIB MRTX849; SAFETY;
D O I：
10.2217/pgs-2021-0045
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：587 / 590
页数：4
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