MK2461 suppress progression of pancreatic cancer disrupting interaction between pancreatic cancer cells and stellate cells

被引:0
|
作者
Inoue, Koetsu [1 ]
Ohtsuka, Hideo [1 ]
Motoi, Fuyuhiko [1 ]
Douchi, Daisuke [1 ]
Kawasaki, Shuhei [1 ]
Kawaguchi, Kei [1 ]
Masuda, Kunihiro [1 ]
Fukase, Koji [1 ]
Ohnuma, Shinobu [1 ]
Naitoh, Takeshi [1 ]
Katayose, Yu [2 ]
Egawa, Shinichi [3 ]
Unno, Michiaki [1 ]
机构
[1] Tohoku Univ, Grad Sch Med, Sendai, Miyagi 980, Japan
[2] Tohoku Univ, Grad Sch Med, Dept Surg, Div Integrated Surg & Oncol, Sendai, Miyagi 980, Japan
[3] Int Res Inst Disaster Sci, Div Int Cooperat Disaster Med, Sendai, Miyagi, Japan
关键词
D O I
10.1158/1538-7445.AM2015-404
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
404
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis
    Xu, Zhihong
    Vonlaufen, Alain
    Phillips, Phoebe A.
    Fiala-Beer, Eva
    Zhang, Xuguo
    Yang, Lu
    Biankin, Andrew V.
    Goldstein, David
    Pirola, Romano C.
    Wilson, Jeremy S.
    Apte, Minoti V.
    AMERICAN JOURNAL OF PATHOLOGY, 2010, 177 (05): : 2585 - 2596
  • [22] Stars and stripes in pancreatic cancer: role of stellate cells and stroma in cancer progression
    Wilson, Jeremy S.
    Pirola, Romano C.
    Apte, Minoti V.
    FRONTIERS IN PHYSIOLOGY, 2014, 5
  • [23] CD10 Positive Pancreatic Stellate Cells Enhance the Progression of Pancreatic Cancer
    Ikenaga, N.
    Ohuchida, K.
    Mizumoto, K.
    Fujiwara, K.
    Kozono, S.
    Ohtsuka, T.
    Nakamura, M.
    Tanaka, M.
    PANCREAS, 2011, 40 (08) : 1328 - 1328
  • [24] Role of pancreatic stellate cells in chemoresistance in pancreatic cancer
    McCarroll, Joshua A.
    Naim, Stephanie
    Sharbeen, George
    Russia, Nelson
    Lee, Julia
    Kavallaris, Maria
    Goldstein, David
    Phillips, Phoebe A.
    FRONTIERS IN PHYSIOLOGY, 2014, 5
  • [25] Gene expression profiling of human pancreatic stellate cells and their roles in pancreatic cancer progression
    Phillips, P. A.
    Chow, E.
    Kaplan, W.
    Cowley, M.
    Vonlaufen, A.
    Yang, L.
    Goldstein, D.
    Pirola, R.
    Wilson, J.
    Apte, M. V.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2009, 24 : A333 - A334
  • [26] Key role of pancreatic stellate cells in pancreatic cancer
    Pothula, Srinivasa P.
    Xu, Zhihong
    Goldstein, David
    Pirola, Romano C.
    Wilson, Jeremy S.
    Apte, Minoti V.
    CANCER LETTERS, 2016, 381 (01) : 194 - 200
  • [27] Targeting Pancreatic Stellate Cells in Cancer
    Schnittert, Jonas
    Bansal, Ruchi
    Prakash, Jai
    TRENDS IN CANCER, 2019, 5 (02): : 128 - 142
  • [28] CD271+ Subpopulation of Pancreatic Stellate Cells Correlates with Prognosis of Pancreatic Cancer and Is Regulated by Interaction with Cancer Cells
    Fujiwara, Kenji
    Ohuchida, Kenoki
    Mizumoto, Kazuhiro
    Shindo, Koji
    Eguchi, Daiki
    Kozono, Shingo
    Ikenaga, Naoki
    Ohtsuka, Takao
    Takahata, Shunichi
    Aishima, Shinichi
    Tanaka, Masao
    PLOS ONE, 2012, 7 (12):
  • [29] CD271+Pancreatic Stellate Cells are Correlated With Prognosis of Patients With Pancreatic Cancer and Regulated by Interaction With Cancer Cells
    Fujiwara, K.
    Ohuchida, K.
    Mizumoto, K.
    Shindo, K.
    Eguchi, D.
    Kozono, S.
    Ikenaga, N.
    Ohtsuka, T.
    Takahata, S.
    Aishima, S.
    Tanaka, M.
    PANCREAS, 2012, 41 (07) : 1146 - 1146
  • [30] The Interaction of pancreatic Cancer and Stellate Cells as a Mediator of Radiation Resistance in ductal Pancreatic Adenocarcinoma
    Mantoni, T. S.
    Lunardi, S.
    McKenna, W. G.
    Brunner, T. B.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2011, 187 : 38 - 39