Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies

被引:77
|
作者
Stuver, Robert [1 ]
Shah, Gunjan L. [2 ]
Korde, Neha S. [3 ]
Roeker, Lindsey E. [4 ]
Mato, Anthony R. [4 ]
Batlevi, Connie L. [1 ]
Chung, David J. [2 ]
Doddi, Sital [5 ]
Falchi, Lorenzo [1 ]
Gyurkocza, Boglarka [2 ]
Hamilton, Audrey [1 ]
Lin, Ya-Hui [5 ]
Jakubowski, Ann A. [2 ]
Joffe, Erel [1 ]
Landau, Heather L. [2 ]
Lin, Richard J. [2 ]
Mailankody, Sham [3 ]
Palomba, M. Lia [1 ]
Park, Jae H. [4 ]
Perales, Miguel-Angel [2 ]
Ponce, Doris M. [2 ]
V. Ramanathan, Lakshmi [5 ]
Salles, Gilles A. [1 ]
Scordo, Michael [2 ]
Seo, Susan K. [6 ]
Shah, Urvi A. [3 ]
Stein, Eytan M. [4 ]
Straus, David [1 ]
Usmani, Saad Z. [3 ]
Young, James W. [2 ]
Zelenetz, Andrew D. [1 ]
Noy, Ariela [1 ]
Vardhana, Santosha A. [1 ,7 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Med, Lymphoma Serv, 1275 York Ave, New York, NY 10021 USA
[2] Mem Sloan Kettering Canc Ctr, Dept Med, Adult Bone Marrow Transplant Serv, 1275 York Ave, New York, NY 10021 USA
[3] Mem Sloan Kettering Canc Ctr, Dept Med, Myeloma Serv, 1275 York Ave, New York, NY 10021 USA
[4] Mem Sloan Kettering Canc Ctr, Dept Med, Leukemia Serv, 1275 York Ave, New York, NY 10021 USA
[5] Mem Sloan Kettering Canc Ctr, Dept Lab Med, 1275 York Ave, New York, NY 10021 USA
[6] Mem Sloan Kettering Canc Ctr, Infect Dis Serv, Div Subspecialty Med, New York, NY 10021 USA
[7] Mem Sloan Kettering Canc Ctr, Human Oncol & Pathogenesis Program, 1275 York Ave, New York, NY 10021 USA
关键词
D O I
10.1016/j.ccell.2022.05.007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:590 / 591
页数:2
相关论文
共 50 条
  • [31] Tixagevimab-Cilgavimab Decreases the Rate of SARS-CoV-2 Infection Among Solid Organ Transplant Recipients
    Sanayei, Ava M.
    Montalvan, Adriana
    Faria, Isabella
    Ochalla, Julia
    Pavlakis, Martha
    Blair, Barbra M.
    Alonso, Carolyn D.
    Curry, Michael
    Saberi, Behnam
    TRANSPLANTATION PROCEEDINGS, 2023, 55 (08) : 1784 - 1792
  • [32] Incidence and Features of SARS-CoV-2 Breakthrough Infection in the Hematological Conditions After Tixagevimab-Cilgavimab Prophylaxis
    Duminuco, Andrea
    Nardo, Antonella
    Orofino, Alessandra
    Giunta, Giuliana
    Conticello, Concetta
    Del Fabro, Vittorio
    Figuera, Amalia
    Chiarenza, Annalisa
    Milone, Giuseppe
    Leotta, Salvatore
    Cupri, Alessandra
    Parisi, Marina
    Mauro, Elisa
    Vetro, Calogero
    Di Raimondo, Francesco
    Romano, Alessandra
    Palumbo, Giuseppe A.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 : S446 - S447
  • [33] COST-EFFECTIVENESS OF AZD7442 (TIXAGEVIMAB AND CILGAVIMAB) FOR PRE-EXPOSURE PROPHYLAXIS AGAINST COVID-19 IN THE IMMUNOCOMPROMISED POPULATION
    Sutton, K.
    Miller, P.
    Branscombe, N.
    Mittal, M.
    Browne, C.
    Arnetorp, S.
    Henry, T.
    Breslin, K.
    Bungey, G.
    Quint, J.
    Montgomery, H.
    VALUE IN HEALTH, 2022, 25 (12) : S168 - S168
  • [34] Efficacy of Tixagevimab and Cilgavimab Against SARS-CoV-2 Infections in Patients with Inborn Errors of Immunity
    Johnson, Sarah
    McDonnell, John C.
    Fernandez, James M.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2023, 43 (05) : 865 - 868
  • [35] Efficacy of Tixagevimab and Cilgavimab Against SARS-CoV-2 Infections in Patients with Inborn Errors of Immunity
    Sarah Johnson
    John C. McDonnell
    James M. Fernandez
    Journal of Clinical Immunology, 2023, 43 (5) : 865 - 868
  • [36] Efficacy of Preexposure Prophylaxis with Monoclonal Antibody Tixagevimab-Cilgavimab against Emerging SARS-CoV-2 Resistant Variants in Patients with Chronic Lymphocytic Leukemia
    Benjamini, Ohad
    Tadmor, Tamar
    Avigdor, Abraham
    Gershon, Rotem
    Kliker, Limor
    Fares, Florin
    Atari, Nofar
    Laevsky, Ilana
    Abdelkader, Bayan
    Hod, Tammy
    Golan-Shany, Orit
    Mandelboim, Michal
    Rahav, Galia
    ACTA HAEMATOLOGICA, 2024, 147 (06) : 634 - 645
  • [37] Safety, Tolerability and Pharmacokinetics of Half-Life Extended Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Monoclonal Antibodies AZD7442 (Tixagevimab-Cilgavimab) in Healthy Adults
    Forte-Soto, Pablo
    Albayaty, Muna
    Brooks, Dennis
    Arends, Rosalinda H.
    Tillinghast, John
    Aksyuk, Anastasia A.
    Bouquet, Jerome
    Chen, Cecil
    Gebre, Asfiha
    Kubiak, Robert J.
    Reddy, Venkatesh Pilla
    Seegobin, Seth
    Streicher, Katie
    Templeton, Alison
    Esser, Mark T.
    JOURNAL OF INFECTIOUS DISEASES, 2023, 227 (10): : 1153 - 1163
  • [38] Effectiveness of AZD7442 (Tixagevimab/Cilgavimab) for Pre-Exposure Prophylaxis Against COVID-19 Hospitalization in Israel During the Omicron Sub-Variant Time Period
    Hayek, Samah
    Levy, Joseph
    Shaham, Galit
    Dagan, Noa
    Serby, Danielle
    Duskin-Bitan, Hadar
    Dube, Sabada
    Ferreira, Catia
    Livnat, Idit
    Talarico, Carla
    Taylor, Sylvia
    Venkatesan, Sudhir
    Yarden, Adva
    Balicer, Ran D.
    Netzer, Doron
    Peretz, Alon
    INFECTIOUS DISEASES AND THERAPY, 2025, 14 (02) : 433 - 445
  • [39] Impact of Sars-CoV-2 Prophylaxis with Tixagevimab-Cilgavimab in High-Risk Patients with B-Cell Malignancies: A Single-Center Retrospective Study
    Assanto, Giovanni Manfredi
    Totaro, Matteo
    Poggiali, Rebecca
    Delli Paoli, Adele
    Annechini, Giorgia
    D'Elia, Gianna Maria
    Aji, Francesco
    Petrucci, Luigi
    Fazio, Francesca
    Del Giudice, Ilaria
    Martelli, Maurizio
    Micozzi, Alessandra
    Gentile, Giuseppe
    MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, 2023, 15 (01)
  • [40] Efficacy and Safety of Tixagevimab-Cilgavimab (Evusheld or AZD7442) As Pre-Exposure Prophylaxis for COVID-19 Among Allogeneic Hematopoietic Stem Cell Transplant Recipients
    Do, Quan
    Bahaj, Waled
    Chandler, Natasha
    Chao, Ju-Hsien
    Emmons, Robert V. B.
    Hegazi, Mohamed
    BLOOD, 2023, 142