Synthetic approaches to Cinchona alkaloids:: the C-8/C-9 disconnection strategy

被引：5

作者：

Jankowski, RL

Joseph, D

Cavé, C

Dumas, F

Ourevitch, M

Mahuteau, J

Morgant, G

Pavlovic, NB

d'Angelo, J

机构：

[1] Univ Paris Sud, CNRS, UMR 8076, Unite Chim Organ,Ctr Etudes Pharmaceut, F-92296 Chatenay Malabry, France

[2] Univ Paris Sud, Ctr Etud Pharmaceut, Lab Cristallochim Bioinorgan, F-92296 Chatenay Malabry, France

[3] Ecole Cent Paris, CNRS, UMR 8580, SPMS, F-92296 Chatenay Malabry, France

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 22期

关键词：

aldols; alkaloids; amines; quinolines; quinuclidines;

D O I：

10.1016/S0040-4039(03)00926-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

When conducted in DMSO, the Hunig's base-promoted condensation of 3-quinuclidinone with quinoline-4-carboxalde-hyde gave an equimolar mixture of epimeric aldols 8 with an excellent yield. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：4187 / 4190

页数：4

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