Synthetic approaches to Cinchona alkaloids:: the C-8/C-9 disconnection strategy

被引：5
|
作者：
Jankowski, RL
Joseph, D
Cavé, C
Dumas, F
Ourevitch, M
Mahuteau, J
Morgant, G
Pavlovic, NB
d'Angelo, J
机构：
[1] Univ Paris Sud, CNRS, UMR 8076, Unite Chim Organ,Ctr Etudes Pharmaceut, F-92296 Chatenay Malabry, France
[2] Univ Paris Sud, Ctr Etud Pharmaceut, Lab Cristallochim Bioinorgan, F-92296 Chatenay Malabry, France
[3] Ecole Cent Paris, CNRS, UMR 8580, SPMS, F-92296 Chatenay Malabry, France
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 22期
关键词：
aldols; alkaloids; amines; quinolines; quinuclidines;
D O I：
10.1016/S0040-4039(03)00926-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
When conducted in DMSO, the Hunig's base-promoted condensation of 3-quinuclidinone with quinoline-4-carboxalde-hyde gave an equimolar mixture of epimeric aldols 8 with an excellent yield. (C) 2003 Elsevier Science Ltd. All rights reserved.
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页码：4187 / 4190
页数：4
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