Impairment of energy metabolism and excitotoxic cell death in Huntington's disease

被引:0
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作者
Young, AB [1 ]
机构
[1] HARVARD UNIV, SCH MED, BOSTON, MA USA
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R74 [神经病学与精神病学];
学科分类号
摘要
The gene for Huntington's disease is widely expressed in brain and yet the illness is characterized pathologically by a distinct regional pattern of cell death. Various theories for this selective vulnerability have been offered but the most compelling remains that of abnormal energy metabolism. These issues are reviewed.
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页码:496 / 498
页数:3
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