Identification and Characterization of Oncogenic SOS1 Mutations in Lung Adenocarcinoma

被引：1
|
作者：
Cai, D. [1 ]
Choi, P. [2 ]
Meyerson, M. [2 ]
机构：
[1] Harvard Univ, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
来源：
JOURNAL OF THORACIC ONCOLOGY | 2017年 / 12卷 / 08期
关键词：
D O I：
10.1016/j.jtho.2017.06.031
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：S1538 / S1539
页数：2
相关论文
共 50 条
  • [21] Germline gain-of-function mutations in SOS1 cause Noonan syndrome
    Roberts, Amy E.
    Araki, Toshiyuki
    Swanson, Kenneth D.
    Montgomery, Kate T.
    Schiripo, Taryn A.
    Joshi, Victoria A.
    Li, Li
    Yassin, Yosuf
    Tamburino, Alex M.
    Neel, Benjamin G.
    Kucherlapati, Raju S.
    NATURE GENETICS, 2007, 39 (01) : 70 - 74
  • [22] Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma
    Baltanas, Fernando C.
    Garcia-Navas, Rosula
    Rodriguez-Ramos, Pablo
    Calzada, Nuria
    Cuesta, Cristina
    Borrajo, Javier
    Fuentes-Mateos, Rocio
    Olarte-San Juan, Andrea
    Vidana, Nerea
    Castellano, Esther
    Santos, Eugenio
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [23] Lead Identification of Novel Naphthyridine Derivatives as Potent SOS1 Inhibitors
    Li, Dongsheng
    Xie, Qing
    Yang, Maozhi
    Cai, Yalei
    Sun, Kang
    Jiang, Shujuan
    Yu, Songda
    Liu, Lei
    Zhang, Yixiang
    Yu, Bing
    Tu, Wangyang
    Li, Leping
    ACS MEDICINAL CHEMISTRY LETTERS, 2024, 15 (06): : 958 - 964
  • [24] Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma
    Imielinski, Marcin
    Greulich, Heidi
    Kaplan, Bethany
    Araujo, Luiz
    Amann, Joseph
    Horn, Leora
    Schiller, Joan
    Villalona-Calero, Miguel A.
    Meyerson, Matthew
    Carbone, David P.
    JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (04): : 1582 - 1586
  • [25] Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome
    Tartaglia, Marco
    Pennacchio, Len A.
    Zhao, Chen
    Yadav, Kamlesh K.
    Fodale, Valentina
    Sarkozy, Anna
    Pandit, Bhaswati
    Oishi, Kimihiko
    Martinelli, Simone
    Schackwitz, Wendy
    Ustaszewska, Anna
    Martin, Joel
    Bristow, James
    Carta, Claudio
    Lepri, Francesca
    Neri, Cinzia
    Vasta, Isabella
    Gibson, Kate
    Curry, Cynthia J.
    Lopez Siguero, Juan Pedro
    Digilio, Maria Cristina
    Zampino, Giuseppe
    Dallapiccola, Bruno
    Bar-Sagi, Dafna
    Gelb, Bruce D.
    NATURE GENETICS, 2007, 39 (01) : 75 - 79
  • [26] Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome
    Marco Tartaglia
    Len A Pennacchio
    Chen Zhao
    Kamlesh K Yadav
    Valentina Fodale
    Anna Sarkozy
    Bhaswati Pandit
    Kimihiko Oishi
    Simone Martinelli
    Wendy Schackwitz
    Anna Ustaszewska
    Joel Martin
    James Bristow
    Claudio Carta
    Francesca Lepri
    Cinzia Neri
    Isabella Vasta
    Kate Gibson
    Cynthia J Curry
    Juan Pedro López Siguero
    Maria Cristina Digilio
    Giuseppe Zampino
    Bruno Dallapiccola
    Dafna Bar-Sagi
    Bruce D Gelb
    Nature Genetics, 2007, 39 : 75 - 79
  • [27] Mutation analysis in a group of patients with Noonan syndrome, new mutations identified in SOS1
    Cisternino, Mariangela
    Longoni, Mauro
    Coi, Paola
    Mannarino, Savina
    Cabano, Rita
    Sirgiovanni, Ida
    Rulfi, Gabriele
    Riva, Paola
    HORMONE RESEARCH, 2008, 70 : 42 - 42
  • [28] Comprehensive Characterization of Oncogenic Drivers in Asian Lung Adenocarcinoma
    Li, Shiyong
    Choi, Yoon-La
    Gong, Zhuolin
    Liu, Xiao
    Lira, Maruja
    Kan, Zhengyan
    Oh, Ensel
    Wang, Jian
    Ting, Jason C.
    Ye, Xiangsheng
    Reinhart, Christoph
    Liu, Xiaoqiao
    Pei, Yunfei
    Zhou, Wei
    Chen, Ronghua
    Fu, Shijun
    Jin, Gang
    Jiang, Awei
    Fernandez, Julio
    Hardwick, James
    Kang, Min Woong
    I, Hoseok
    Zheng, Hancheng
    Kim, Jhingook
    Mao, Mao
    JOURNAL OF THORACIC ONCOLOGY, 2016, 11 (12) : 2129 - 2140
  • [29] Loss of Halophytism by Interference with SOS1 Expression
    Oh, Dong-Ha
    Leidi, Eduardo
    Zhang, Quan
    Hwang, Sung-Min
    Li, Youzhi
    Quintero, Francisco J.
    Jiang, Xingyu
    D'Urzo, Matilde Paino
    Lee, Sang Yeol
    Zhao, Yanxiu
    Bahk, Jeong Dong
    Bressan, Ray A.
    Yun, Dae-Jin
    Pardo, Jose M.
    Bohnert, Hans J.
    PLANT PHYSIOLOGY, 2009, 151 (01) : 210 - 222
  • [30] Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development
    Wang, DZM
    Hammond, VE
    Abud, HE
    Bertoncello, I
    McAvoy, TW
    Bowtell, DDL
    GENES & DEVELOPMENT, 1997, 11 (03) : 309 - 320
12345