Camptothecin and mitomycin combination chemotherapy on ovarian clear cell carcinoma with multiple systemic metastases

被引:0
|
作者
Tanaka, T [1 ]
Umesaki, N [1 ]
Ogita, S [1 ]
机构
[1] Osaka City Univ, Sch Med, Dept Obstet & Gynecol, Abeno Ku, Osaka 5458585, Japan
关键词
camptothecin; mitomycin; clear cell carcinoma; ovary; chemotherapy;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Ovarian clear cell carcinoma is known for decreased responsiveness to most anticancer drugs, and the prognosis of patients with ovarian clear cell tumors is very poor. We report such a patient with multiple systemic metastases who showed a complete response to combined camptothecin and mitomycin chemotherapy. During therapy, clinical drug-resistance was observed transiently, but response was restored by intermittent administrations of camptothecin. Such combination chemotherapy may be a useful alternative regimen for advanced and/or metastatic ovarian clear cell carcinoma.
引用
收藏
页码:377 / 379
页数:3
相关论文
共 50 条
  • [31] COMBINATION CHEMOTHERAPY OF ADVANCED OVARIAN-CARCINOMA
    KLEINMANNS, G
    DAUER, W
    KNIEF, JJ
    WESTERHAUSEN, M
    BLUT, 1982, 45 (03): : 174 - 174
  • [32] Multiple metastases of renal clear cell carcinoma within adenomatous nodule in multinodular goiter
    Tamponi, E.
    Faa, G.
    Soddu, S.
    Senes, G.
    Calo, P. G.
    Lai, M. L.
    VIRCHOWS ARCHIV, 2012, 461 : S104 - S105
  • [33] Molecular portraits of clear cell ovarian and endometrial carcinoma with comparison to clear cell renal cell carcinoma
    Ackroyd, Sarah A.
    Arguello, David
    Ramos, Pilar
    Mahdi, Haider
    ElNaggar, Adam
    Winer, Ira
    Holloway, Rob
    Krivak, Thomas
    Jones, Nathaniel
    Turner, Valerie Galvan
    Herzog, Thomas
    Chu, Christina
    Brown, Jubilee
    Mantia-Smaldone, Gina
    GYNECOLOGIC ONCOLOGY, 2023, 169 : 164 - 171
  • [34] Molecular portraits of clear cell ovarian and endometrial carcinoma with comparison to clear cell renal cell carcinoma
    Mantia-Smaldone, G. M.
    Arguello, D.
    Mahdi, H.
    ElNaggar, A. C.
    Winer, I.
    Holloway, R. W.
    Krivak, T. C.
    Jones, N. L.
    Galvan-Turner, V.
    Herzog, T. J.
    Chu, C.
    Brown, J.
    GYNECOLOGIC ONCOLOGY, 2019, 154 : 175 - 175
  • [35] Ovarian clear cell carcinoma in Cowden Syndrome
    Yauy, K.
    Imbert-Bouteille, M.
    Bubien, V.
    Lindet-Bourgeois, C.
    Rathat, G.
    Perrochia, H.
    MacGrogan, G.
    Bessis, D.
    Tinat, J.
    Baert-Desurmont, S.
    Blanluet, M.
    Vande Perre, P.
    Baudry, K.
    Pujol, P.
    Corsini, C.
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2019, 27 : 1558 - 1559
  • [36] Leiomyosarcoma with Synchronous Clear Cell Ovarian Carcinoma
    Rettenmaier, Mark
    Epstein, Howard D.
    Abaid, Lisa N.
    Bechtol, Karen A.
    Goldstein, Bram H.
    ONKOLOGIE, 2010, 33 (12): : 695 - 697
  • [37] Tumor heterogeneity in ovarian clear cell carcinoma
    Huang, Ruby Yun-Ju
    CANCER RESEARCH, 2024, 84 (05)
  • [38] Translational genomics of ovarian clear cell carcinoma
    Khalique, Saira
    Lord, Christopher J.
    Banerjee, Susana
    Natrajan, Rachael
    SEMINARS IN CANCER BIOLOGY, 2020, 61 : 121 - 131
  • [39] The unique metabolome of clear cell ovarian carcinoma
    Ji, Jennifer X.
    Hoang, Lien N.
    Cochrane, Dawn R.
    Lum, Amy
    Senz, Janine
    Farnell, David
    Tessier-Cloutier, Basile
    Huntsman, David G.
    Geltink, Ramon I. Klein
    JOURNAL OF PATHOLOGY, 2024, 264 (02): : 160 - 173
  • [40] Ovarian clear cell carcinoma - An examination of relapses
    Nguyen, P.
    Wong, F.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2008, 56 (01) : 225 - 226