Hydrogenation of butane-2,3-dione with heterogeneous cinchona modified platinum catalysts: a combination of an enantioselective reaction and kinetic resolution

被引：53

作者：

Studer, M ^{[1
]}

Okafor, V

Blaser, HU

机构：

[1] Novartis Serv AG, Sci Serv, CH-4002 Basel, Switzerland

[2] Univ Witwatersrand, Dept Chem, Johannesburg, South Africa

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 09期

关键词：

D O I：

10.1039/a801390j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(R)-3-Hydroxybutan-2-one was obtained with 85-90% ee albeit in low yield by the Pt/Al2O3 cinchona catalyzed hydrogenation of butane-2,3-dione by a combination of enantioselective hydrogenation and kinetic resolution.

引用

页码：1053 / 1054

页数：2

相关论文

共 33 条

[31] 98% enantioselectivity in the asymmetric synthesis of a useful chiral building block by heterogeneous method:: Enantioselective hydrogenation of ethyl-benzoylformate over cinchona modified Pt/Al2O3 catalysts in the acetic acid
Sutyinszki, M
Szöri, K
Felföldi, K
Bartók, M
CATALYSIS COMMUNICATIONS, 2002, 3 (03) : 125 - 127
[32] INTERMEDIATE PRODUCTS OF THE REACTION OF (4,4,9,9-TETRAMETHYL-5,8-DIAZADODECANE-2,11-DIONE DIHYDRAZONE)NICKEL(II) WITH BUTANE-2,3-DIONE - THE STRUCTURE OF CIS-AQUA(3,4,7,9,9,14,14,16-OCTAMETHYL-1,2,5,6,10,13-HEXAAZACYCLOHEXADECA-1(16),4,6-TIEN-3-OL)NICKEL(II) PERCHLORATE TRIHYDRATE
CURTIS, NF
DAVIS, AR
EINSTEIN, FWB
AUSTRALIAN JOURNAL OF CHEMISTRY, 1994, 47 (10) : 1885 - 1899
[33] Intermediate products of the reaction of (4,4,9,9-tetramethyl-5,8- diazadodecane- 2,11-dione dihydrazone) nickel(II) with butane-2,3-dione; the structure of cis-aqua (3,4,7,9,9,14,14,16- octamethyl-1,2,5,6,10,13- hexaazacyclohexadeca- 1(16),4,6-trien-3-ol) nickel(II) perchlorate trihydrate
Curtis, Neil F.
Davis, Alan R.
Einstein, Frederick W.B.
Australian Journal of Chemistry, 1994, 47 (10)

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