Transition-metal-free synthesis of β-trifluoromethylated enamines with trifluoromethanesulfinate

被引：42

作者：

Jiang, Huanfeng ^{[1
]}

Huang, Wei ^{[1
]}

Yu, Yue ^{[1
]}

Yi, Songjian ^{[1
]}

Li, Jiawei ^{[1
]}

Wu, Wanqing ^{[1
]}

机构：

[1] South China Univ Technol, Key Lab Funct Mol Engn Guangdong Prov, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 54期

基金：

中国国家自然科学基金;

关键词：

COPPER-CATALYZED TRIFLUOROMETHYLATION; ALPHA; BETA-UNSATURATED CARBOXYLIC-ACIDS; LIGHT PHOTOREDOX CATALYSIS; C BOND FORMATION; OXIDATIVE TRIFLUOROMETHYLATION; ROOM-TEMPERATURE; SODIUM TRIFLUOROMETHANESULFINATE; MEDICINAL CHEMISTRY; POLYSUBSTITUTED PYRROLES; HETEROAROMATIC-COMPOUNDS;

D O I：

10.1039/c7cc03125d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have developed a transition-metal free trifluoromethylation protocol between enamines and CF3SO2Na. A wide range of beta-trifluoromethyl substituted enamines were delivered in moderate to high yields with only E-configurations.

引用

页码：7473 / 7476

页数：4

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