Transition-metal-free synthesis of β-trifluoromethylated enamines with trifluoromethanesulfinate

被引：42
|
作者：
Jiang, Huanfeng [1 ]
Huang, Wei [1 ]
Yu, Yue [1 ]
Yi, Songjian [1 ]
Li, Jiawei [1 ]
Wu, Wanqing [1 ]
机构：
[1] South China Univ Technol, Key Lab Funct Mol Engn Guangdong Prov, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 54期
基金：
中国国家自然科学基金;
关键词：
COPPER-CATALYZED TRIFLUOROMETHYLATION; ALPHA; BETA-UNSATURATED CARBOXYLIC-ACIDS; LIGHT PHOTOREDOX CATALYSIS; C BOND FORMATION; OXIDATIVE TRIFLUOROMETHYLATION; ROOM-TEMPERATURE; SODIUM TRIFLUOROMETHANESULFINATE; MEDICINAL CHEMISTRY; POLYSUBSTITUTED PYRROLES; HETEROAROMATIC-COMPOUNDS;
D O I：
10.1039/c7cc03125d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have developed a transition-metal free trifluoromethylation protocol between enamines and CF3SO2Na. A wide range of beta-trifluoromethyl substituted enamines were delivered in moderate to high yields with only E-configurations.
引用
收藏
页码：7473 / 7476
页数：4
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