Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless

被引：190
|
作者：
Grimm, S [1 ]
Pflugfelder, GO [1 ]
机构：
[1] UNIV WURZBURG,THEODOR BOVERI INST,BIOZENTRUM,LEHRSTUHL GENET,D-97074 WURZBURG,GERMANY
来源：
SCIENCE | 1996年 / 271卷 / 5255期
关键词：
D O I：
10.1126/science.271.5255.1601
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Diffusible factors of several protein families control appendage outgrowth and patterning in both insects and vertebrates. In Drosophila wing development, the gene decapentaplegic (dpp) is expressed along the anteroposterior compartment boundary. Early wingless (wg) expression is involved in setting up the dorsoventral boundary. Interaction between dpp- and wg-expressing cells promotes appendage outgrowth. Here, it is shown that optomotor-blind (omb) expression is required for distal wing development and is controlled by both dpp and wg. Ectopic omb expression can lead to the growth of additional wings. Thus, omb is essential for wing development and is controlled by two signaling pathways.
引用
收藏
页码：1601 / 1604
页数：4
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