BINOL diesters as useful building blocks towards chiral macrocyclic compounds

被引:4
|
作者
Pikus, Grzegorz [1 ]
Jurczak, Janusz [1 ]
机构
[1] Polish Acad Sci, Inst Organ Chem, Kasprzaka 44-52, PL-01224 Warsaw, Poland
关键词
BINOL; Chirality; Double-amidation reaction; Macrocyclic amides; Static combinatorial libraries; ANION-BINDING; RECEPTORS; RECOGNITION; LIGANDS; TRANSPORT; LIBRARY; EPOXIDATION; SUBSTRATE; VERSATILE; PROTEIN;
D O I
10.1016/j.tet.2016.02.051
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Double-amidation reaction of (R)- or (5)-2,2'-([1,1'-binaphthalene]-2,2'-diylbis(oxy))diacetic dimethyl ester with five differing in length am-diaminoethers were used for the synthesis of chiral macrocyclic compounds of different size of the cavity, potential receptors of various chiral guests. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1928 / 1932
页数:5
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