Manganese-Catalyzed Direct Olefination of Methyl-Substituted Heteroarenes with Primary Alcohols

被引：96

作者：

Barman, Milan K. ^{[1
]}

Waiba, Satyadeep ^{[1
]}

Maji, Biplab ^{[1
]}

机构：

[1] Indian Inst Sci Educ & Res Kolkata, Dept Chem Sci, Mohanpur 741246, India

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2018年 / 57卷 / 29期

关键词：

dehydrogenative coupling; heteroarenes; manganese; olefination; pincer ligands; ASYMMETRIC TRANSFER HYDROGENATION; C BOND FORMATION; SUSTAINABLE SYNTHESIS; PINCER COMPLEXES; STYRYL DYES; AMINES; DEHYDROGENATION; ALKYLATION; KETONES; IRON;

D O I：

10.1002/anie.201804729

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we present the first catalytic direct olefination of methyl-substituted heteroarenes with primary alcohols through an acceptorless dehydrogenative coupling. The reaction is catalyzed by a complex of the earth-abundant transition metal manganese that is stabilized by a bench-stable NNN pincer ligand derived from 2-hydrazinylpyridine. The reaction is environmentally benign, producing only hydrogen and water as byproducts. A large number of E-disubstituted olefins were selectively obtained with high efficiency.

引用

页码：9126 / 9130

页数：5

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