Crystal structure of 2,8-dimethyl-3-chloro-4H-pyrido[1,2-a]pyrimidin-4-one

被引：1
|
作者：
Anthal, S. [1 ]
Dutt, P. [2 ]
Satti, N. K. [2 ]
Kant, R. [1 ]
Gupta, V. K. [1 ]
机构：
[1] Univ Jammu, Postgrad Dept Phys & Elect, Jammu 180006, India
[2] Indian Inst Integrat Med, Nat Prod Chem Div, Jammu 180001, India
来源：
CRYSTALLOGRAPHY REPORTS | 2014年 / 59卷 / 07期
关键词：
RECEPTOR ANTAGONISTS; DERIVATIVES; INHIBITORS; SOLUBILITY;
D O I：
10.1134/S1063774514070025
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, 2,8-dimethyl-3-chloro-4H-pyrido[1,2-a]pyrimidin-4-one, (C10H9ClN2O), was synthesized, and its structure was established by spectral analysis and X-ray diffraction studies. There are two independent molecules per asymmetric unit. In both the molecules, the pyrido-pyrimidine moiety is planar with a dihedral angle of 3.53(9)A degrees for molecule A and 1.61(9)A degrees for molecule B. The crystal structure is stabilized by C-Ha <-O and C-Ha <-Cl hydrogen bonds. The pi-pi interactions were also observed between the A and B molecules. The pyrido-pyrimidine moiety is not involved in any C-Ha <-pi contacts.
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页码：1005 / 1009
页数：5
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