Wnt Signaling Pathway in Schizophrenia

被引：17
|
作者：
Peng, Yanmin [1 ]
Xu, Yifeng [1 ]
Cui, Donghong [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Key Lab Translat Psychiat, Shanghai 200030, Peoples R China
来源：
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS | 2014年 / 13卷 / 05期
基金：
中国国家自然科学基金;
关键词：
Adenomatous polyposis coli; glycogen synthase kinase-3; schizophrenia; Wnt signaling pathway; ADENOMATOUS-POLYPOSIS-COLI; MEDIAL PREFRONTAL CORTEX; SENSITIZED ANIMALS SHOW; LONG-TERM POTENTIATION; RECEPTOR SUBUNIT GENE; FRIZZLED-3; FZD3; GENE; BETA-CATENIN; WNT/BETA-CATENIN; VENTRAL MIDBRAIN; TRANSGENIC MICE;
D O I：
10.2174/1871527312666131223113521
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better understanding of the Wnt pathway might contribute to developing new and more effective tools for diagnosis and treatment of schizophrenia.
引用
收藏
页码：755 / 764
页数：10
相关论文
共 50 条
  • [21] Wnt signaling pathway in retinal vascularization
    Drenser, Kimberly A.
    EYE AND BRAIN, 2016, 8 : 141 - 146
  • [22] Wnt signaling pathway and lung disease
    Van Scoyk, Michelle
    Randall, Jessica
    Sergew, Amen
    Williams, Lisa M.
    Tennis, Meredith
    Winn, Robert A.
    TRANSLATIONAL RESEARCH, 2008, 151 (04) : 175 - 180
  • [23] Implication of Galectinin Wnt signaling pathway
    Shimura, Tatsuo
    Tsutsumi, Souichi
    Suehiro, Taketoshi
    Suzuki, Hideki
    Raz, Avraham
    Kuwano, Hiroyuki
    CLINICAL & EXPERIMENTAL METASTASIS, 2007, 24 (04) : 265 - 266
  • [24] The Wnt/Frizzled GPCR Signaling Pathway
    Katanaev, V. L.
    BIOCHEMISTRY-MOSCOW, 2010, 75 (12) : 1428 - 1434
  • [25] The Wnt Signaling Pathway in Diabetic Nephropathy
    Wang, Haiying
    Zhang, Ran
    Wu, Xinjie
    Chen, Yafen
    Ji, Wei
    Wang, Jingsuo
    Zhang, Yawen
    Xia, Yong
    Tang, Yiqun
    Yuan, Jinxiang
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 9
  • [26] Characterisation of Wnt Signaling Pathway in Rhabdomyosarcoma
    Rao, A. S.
    Cialfi, S.
    Dominici, C.
    Yao, S.
    Foster, C. S.
    Kokai, G.
    Helliwell, T. R.
    McDowell, H. P.
    JOURNAL OF PATHOLOGY, 2011, 224 : S16 - S16
  • [27] Regulation of β-catenin signaling in the Wnt pathway
    Kikuchi, A
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 268 (02) : 243 - 248
  • [28] The Wnt signaling pathway and bone metabolism
    Johnson, Mark L.
    Kamel, Mohamed A.
    CURRENT OPINION IN RHEUMATOLOGY, 2007, 19 (04) : 376 - 382
  • [29] The Wnt signaling pathway and rheumatoid arthritis
    Rabelo, Francieli de Sousa
    Henrique da Mota, Licia Maria
    Correa Lima, Rodrigo Aires
    Correa Lima, Francisco Aires
    Barra, Gustavo Barcelos
    de Carvalho, Jozelio Freire
    Amato, Angelica Amorim
    AUTOIMMUNITY REVIEWS, 2010, 9 (04) : 207 - 210
  • [30] Role of the Wnt signaling pathway in keratoacanthoma
    Joshi, Sarita
    De Angelis, Paula M.
    Zucknick, Manuela
    Schjolberg, Aasa R.
    Andersen, Solveig Norheim
    Clausen, Ole Petter F.
    CANCER REPORTS, 2020, 3 (02)
12345