Ceruloplasmin and what it might do

被引:117
|
作者
Healy, J. [1 ]
Tipton, K. [1 ]
机构
[1] Trinity Coll Dublin, Sch Biochem & Immunol, Dept Biochem, Dublin 2, Ireland
关键词
ceruloplasmin; copper; amine oxidase; ferroxidase; iron; catechol oxidase;
D O I
10.1007/s00702-007-0687-7
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The blue coloured plasma protein ceruloplasmin binds up to 95% of circulating copper, and has several possible functions. It has been proposed to function in copper transport, oxidation of organic amines, iron(II) oxidation and the regulation of cellular iron levels, and catechols, radical scavenging and other antioxidant processes. This account will consider the relative importance of these multiple functions in terms of the physiological roles of ceruloplasmin.
引用
收藏
页码:777 / 781
页数:5
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