Problem-solving therapy versus supportive therapy in geriatric major depression with executive dysfunction

被引:176
|
作者
Alexopoulos, GS
Raue, P
Areán, P
机构
[1] Cornell Univ, Inst Geriatr Psychiat, White Plains, NY 10605 USA
[2] Cornell Univ, Weill Med Coll, Ithaca, NY 14853 USA
[3] Univ Calif San Francisco, San Francisco, CA 94143 USA
来源
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | 2003年 / 11卷 / 01期
关键词
D O I
10.1176/appi.ajgp.11.1.46
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objective: The authors compared the efficacy of problem-solving therapy (PST) and supportive therapy (ST) in a group of elderly subjects with impairment in executive functions. This group was targeted because it has been shown to be at the risk for poor response to pharmacotherapy, Methods: A total of 25 elderly subjects with major depression and abnormal scores in initiation/perseveration and response inhibition tasks were randomly assigned to receive weekly sessions of PST or ST for 12 weeks. The subjects were systematically evaluated by raters blind to the study hypotheses. Results: PST was more effective than ST in leading to remission of depression, fewer post-treatment depressive symptoms, and less disability. A substantial part of the change in depression and disability was explained by the subjects' improvement of skills in generating alternatives and in decision-making. Conclusion: This preliminary study suggests that PST is effective in reducing depressive symptoms and disability in elderly patients with major depression and executive dysfunction. If these findings are confirmed, PST may become an important therapeutic alternative for a patient population who may otherwise remain symptomatic and disabled.
引用
收藏
页码:46 / 52
页数:7
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