Current Concepts: Management of Varices and Variceal Hemorrhage in Cirrhosis.

被引:645
|
作者
Garcia-Tsao, Guadalupe [1 ]
Bosch, Jaime [2 ]
机构
[1] Yale Univ, Sch Med, Sect Digest Dis, New Haven, CT 06520 USA
[2] Univ Barcelona, Hosp Clin, Hepat Hemodynam Lab, Liver Unit, Barcelona, Spain
来源
NEW ENGLAND JOURNAL OF MEDICINE | 2010年 / 362卷 / 09期
关键词
PORTAL HYPERTENSIVE GASTROPATHY; RANDOMIZED CONTROLLED-TRIAL; VENOUS-PRESSURE GRADIENT; INTRAHEPATIC PORTOSYSTEMIC SHUNT; SMALL ESOPHAGEAL-VARICES; NATURAL-HISTORY; PHARMACOLOGICAL-TREATMENT; CYANOACRYLATE INJECTION; ENDOSCOPIC TREATMENT; BAND LIGATION;
D O I
10.1056/NEJMra0901512
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gastroesophageal varices are present at diagnosis in almost half of patients with cirrhosis, and variceal hemorrhage continues to be a lethal complication of cirrhosis. This review explains the three main challenges in clinical management: primary prophylaxis to prevent a first episode of hemorrhage, the treatment of acute bleeding episodes, and secondary prophylaxis to prevent recurrence of variceal hemorrhage. Copyright © 2010 Massachusetts Medical Society.
引用
收藏
页码:823 / 832
页数:10
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