Stereospecific synthesis of azetidine-cis-2,3-dicarboxylic acid

被引:12
|
作者
Arakawa, Y [1 ]
Murakami, T [1 ]
Arakawa, Y [1 ]
Yoshifuji, S [1 ]
机构
[1] Hokuriku Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 9201181, Japan
关键词
azetidine-cis-2,3-dicarboxylic acid; 1,2-dihydropyridine; ruthenium tetroxide; 2-(methoxycarbonyl)-2-azabicyclo[2.2.0]hex-5-ene;
D O I
10.1248/cpb.51.96
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Electrocyclic reaction product of 1-(methoxycarbonyl)-1,2-dihydropyridine was stereospecifically converted by RuO4 oxidation into azetidine-cis-2,3-dicarboxylic acid.
引用
收藏
页码:96 / 97
页数:2
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