Effectiveness of Whole, Inactivated, Low Pathogenicity Influenza A( H7N9) Vaccine against Antigenically Distinct, Highly Pathogenic H7N9 Virus

被引：10
|
作者：
Hatta, Masato [1 ]
Zhong, Gongxun [2 ]
Chiba, Shiho [2 ]
Lopes, Tiago J. S. [2 ]
Neumann, Gabriele [2 ]
Kawaoka, Yoshihiro [2 ,3 ]
机构：
[1] Univ Wisconsin, Influenza Res Inst, Madison, WI USA
[2] Univ Wisconsin, Madison, WI USA
[3] Univ Tokyo, Tokyo, Japan
来源：
EMERGING INFECTIOUS DISEASES | 2018年 / 24卷 / 10期
关键词：
5TH EPIDEMIC; CHINA;
D O I：
10.3201/eid2410.180403
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The recent emergence of highly pathogenic influenza A(H7N9) variants poses a great risk to humans. We show that ferrets vaccinated with low pathogenicity H7N9 virus vaccine do not develop severe symptoms after infection with an antigenically distinct, highly pathogenic H7N9 virus. These results demonstrate the protective benefits of this H7N9 vaccine.
引用
收藏
页码：1910 / 1913
页数：4
相关论文
共 50 条
  • [41] Update on Influenza A(H7N9) Outbreak
    不详
    CLINICAL INFECTIOUS DISEASES, 2013, 57 (04) : I - I
  • [42] Atypical H7N9 avian influenza
    Joob, Beuy
    Wiwanitkit, Viroj
    CHINESE MEDICAL JOURNAL, 2014, 127 (13) : 2491 - 2491
  • [43] Phylogenetic and evolutionary analysis of influenza A H7N9 virus
    Babakir-Mina, Muhammed
    Dimonte, Salvatore
    Lo Presti, Alessandra
    Cella, Eleonora
    Perno, Carlo Federico
    Ciotti, Marco
    Ciccozzi, Massimo
    NEW MICROBIOLOGICA, 2014, 37 (03): : 369 - 376
  • [44] Antigenic Drift of Influenza A(H7N9) Virus Hemagglutinin
    Ning, Tingting
    Nie, Jianhui
    Huang, Weijin
    Li, Changgui
    Li, Xuguang
    Liu, Qiang
    Zhao, Hui
    Wang, Youchun
    JOURNAL OF INFECTIOUS DISEASES, 2019, 219 (01): : 19 - 25
  • [45] Immunity to the newly emerged A/H7N9 influenza virus
    Wang, Z.
    Wan, Y.
    Zhang, A.
    Qiu, C.
    Quinones-Parra, S.
    Loh, L.
    Nguyen, O.
    Ren, Y.
    Thomas, P.
    Inouye, M.
    Zhang, X.
    Doherty, P.
    Xu, J.
    Kedzierska, K.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 46 : 623 - 623
  • [46] Atypical H7N9 avian influenza
    Beuy Joob
    Viroj Wiwanitkit
    中华医学杂志（英文版）, 2014, (13) : 2491 - 2491
  • [47] Novel human H7N9 influenza virus in China
    Wang, Chengmin
    Luo, Jing
    Wang, Jing
    Su, Wen
    Gao, Shanshan
    Zhang, Min
    Xie, Li
    Ding, Hua
    Liu, Shelan
    Liu, Xiaodong
    Chen, Yu
    Jia, Yaxiong
    He, Hongxuan
    INTEGRATIVE ZOOLOGY, 2014, 9 (03): : 372 - 375
  • [48] A novel avian H7N9 influenza virus:The discovery,infectivity,transmissibility and pathogenicity
    Science Foundation in China, 2013, (02) : 31 - 31
  • [49] Nosocomial transmission of avian influenza virus A (H7N9)
    van der Sande, Marianne A. B.
    van der Hoek, Wim
    BMJ-BRITISH MEDICAL JOURNAL, 2015, 351
  • [50] Sex differences in H7N9 influenza A virus pathogenesis
    Hoffmann, Julia
    Otte, Anna
    Thiele, Swantje
    Lotter, Hannelore
    Shu, Yuelong
    Gabriel, Guelsah
    VACCINE, 2015, 33 (49) : 6949 - 6954
12345