Deceptive nasal NK/T-cell lymphoma

被引:7
|
作者
Thakur, Jagdeep S. [1 ]
Mahajan, Aditi [1 ]
Saluja, Manika [1 ]
Mohindroo, Narinder K. [1 ]
机构
[1] Indira Gandhi Med Coll, Dept Otolaryngol Head & Neck Surg ENT, Shimla, HP, India
关键词
Extranodal NK-T-cell Lymphoma; Nose; Sinusitis; Diagnosis; Fungal pathology; Lethal midline granuloma; NATURAL KILLER/T-CELL; SINONASAL;
D O I
10.1177/0049475516684088
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Nasal NK/T cell lymphoma is rare and it easily masquerades as chronic rhinosinusitis. It has a very poor prognosis and hence early diagnosis, although difficult, is necessary for better outcome. We present a case of a 30-year-old man who presented with nasal obstruction, facial oedema and crusts. High-resolution computed tomography found soft tissue in all sinuses and the nasal cavity. Endoscopic biopsy revealed necrotic and inflammatory tissue with fungi on culture. A diagnosis of fungal rhinosinusitis was made but the patient did not respond to antifungal drugs. A histopathology review with immunohistochemistry suggested nasal NK/T cell lymphoma. The patient was started on chemotherapy but died within 1 week.
引用
收藏
页码:268 / 271
页数:4
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