A sensitive voltammetric sensor for taxifolin based on graphene nanosheets with certain orientation modified glassy carbon electrode

The electrodeposition of reduced graphene oxide (ERGO) film with preferred vertical orientation was fabricated on a glassy carbon electrode by using pulse potential method in a graphene oxide colloidal solution. Using square wave adsorptive stripping voltammetry (SWASV), the ERGO film was applied for the first time, in developing a high-sensitive electrochemical sensor for detection of taxifolin. Compared with bare glassy carbon electrode (GCE), the resulting electrodes (ERGO/GCE) exhibited excellent response toward the redox of taxifolin by significantly enhancing the redox peak currents and decreasing the peak-to-peak separation. Under the selected conditions, the peak currents were linear relationship with taxifolin concentration in the range of 1.0 x 10(-8)-1.0 x 10(-6)mol L-1, with detection limit of 2.0 x 10(-9)mol L-1. Besides, the ERGO/GCE also exhibited an excellent selectivity, stability, reproducibility and repeatability. (C) 2014 Elsevier B.V. All rights reserved.