Stability-based model order selection in clustering with applications to gene expression data

被引:0
|
作者
Roth, V [1 ]
Braun, ML [1 ]
Lange, T [1 ]
Buhmann, JM [1 ]
机构
[1] Univ Bonn, Inst Comp Sci, Dept 3, D-53117 Bonn, Germany
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中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
The concept of cluster stability is introduced to assess the validity of data partitionings found by clustering algorithms. It allows us to explicitly quantify the quality of a clustering solution, without being dependent on external information. The principle of maximizing the cluster stability can be interpreted as choosing the most self-consistent data partitioning. We present an empirical estimator for the theoretically derived stability index, based on resampling. Experiments are conducted on well known gene expression data sets, re-analyzing the work by Alon et al. [1] and by Spellman et al. [8].
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页码:607 / 612
页数:6
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