Solid phase approach to muscone synthesis:: Rh(I)-catalyzed hydroformylation of a 1,1-disubstituted alkene on the multipin™ system

被引：18
|
作者：
Takahashi, T [1 ]
Ebata, S [1 ]
Doi, T [1 ]
机构：
[1] Tokyo Inst Technol, Dept Chem Engn, Tokyo 152, Japan
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 11期
关键词：
D O I：
10.1016/S0040-4039(97)10847-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Rh(I)-catalyzed hydroformylation of a polymer-supported 1,1-disubstituted alkene was carried out on the Multipin(TM) system. The reaction proceeded under 75 atm of syngas (H-2 : CO = 1 : 1) providing the corresponding aldehyde on the solid support. Optimization of the reaction conditions is described. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1369 / 1372
页数：4
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