Synthesis of 3-substituted quinolines by ruthenium-catalyzed aza-Michael addition and intramolecular annulation of enaminones with anthranils

被引：11

作者：

Yan, Kelu ^{[1
]}

Liu, Min ^{[1
]}

Wen, Jiangwei ^{[1
]}

Liu, Xiao ^{[1
]}

Wang, Xiaoyu ^{[1
]}

Sui, Xinlei ^{[1
]}

Shang, Wenda ^{[1
]}

Wang, Xiu ^{[1
]}

机构：

[1] Qufu Normal Univ, Sch Chem & Chem Engn, Key Lab Life Organ Anal Shandong Prov, Qufu 273165, Shandong, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2022年 / 46卷 / 16期

基金：

中国国家自然科学基金;

关键词：

SULFOXONIUM YLIDES; FUNCTIONALIZATION; RECOGNITION; CYCLIZATION; MECHANISM; NITRILES; ANILINE; KETONES; ALKYNES; FACILE;

D O I：

10.1039/d2nj00663d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ruthenium-catalyzed aza-Michael addition and intramolecular annulation of enaminones with anthranils to access substituted quinolines has been realized efficiently under simple and easy-to-operate conditions. The reaction substrates in this transformation are different from those in the traditional methods in which anilines are often employed. Most of the products were obtained in good yields. This method offers an alternative approach for the synthesis of 3-arylformyl substituted quinoline derivatives.

引用

页码：7329 / 7333

页数：5

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