Microfluidic control of fluorescence resonance energy transfer: Breaking the FRET limit

被引：45
|
作者：
Zhang, Chun-yang
Johnson, Lawrence W. [1 ]
机构：
[1] CUNY York Coll, Dept Chem, Jamaica, NY 11451 USA
[2] CUNY, Grad Ctr, Jamaica, NY 11451 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 19期
关键词：
D O I：
10.1002/anie.200604861
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
No empty FRET: The microfluidic control of fluorescence resonance energy transfer (FRET) has been demonstrated, and the FRET limit has been broken with a quantum-dot (QD)-based DNA nanosensor in a microfluidic flow. This nanosensor can detect long nucleic acids that have separation distances far beyond the range of FRET and whose detection is not feasible with conventional FRET-based assays. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
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页码：3482 / 3485
页数：4
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