Pilot data of serum proteins from children with autism spectrum disorders

被引：4

作者：

Kaysheva, Anna L. ^{[1
]}

Stepanov, Alexander A. ^{[1
]}

Kopylov, Artur T. ^{[1
]}

Butkova, Tatiana V. ^{[1
]}

Pleshakova, Tatyana ^{[1
]}

Ryabtsev, Vasily V. ^{[1
]}

Iourov, Ivan Yu. ^{[2
]}

Vorsanova, Svetlana G. ^{[3
]}

Ivanov, Yuri D. ^{[1
]}

机构：

[1] Inst Biomed Chem, Moscow, Russia

[2] Mental Hlth Res Ctr, Moscow, Russia

[3] Pirogov Russian Natl Res Med Univ, Veltischev Res & Clin Inst Pediat, Moscow, Russia

来源：

DATA IN BRIEF | 2019年 / 27卷

基金：

俄罗斯科学基金会;

关键词：

Autism spectrum disorder; Panoramic mass spectrometry; Label-free quantitative analysis;

D O I：

10.1016/j.dib.2019.104558

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Protein profiles of 13 serum samples from children with autism spectrum disorders (ASD) and 11 serum samples from healthy volunteers was obtained using panoramic ultra-high resolution mass spectrometry. The analysis of measurements was performed using the proteomics search engine. We identified a group of 74 proteins which we term a "protein fingerprint" specific for serum samples collected from children with autism. Components of the protein fingerprint are involved in hemostasis maintenance including biological regulation, the response to stimulus, regulation of metabolism, and proteins of the immune system. (c) 2019 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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