Convenient synthesis of an N-(1-alkoxyl-9-fluorenyl)serine acridine conjugate

被引：4
|
作者：
Dai, Jifeng [1 ]
Zhou, Qibing [1 ]
机构：
[1] Virginia Commonwealth Univ, Dept Chem, Richmond, VA 23284 USA
来源：
SYNTHETIC COMMUNICATIONS | 2007年 / 37卷 / 1-3期
关键词：
acridine conjugate; 1-alkoxyl-9-fluorenylamine; serine;
D O I：
10.1080/00397910600978531
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report here the synthesis of an N-(1-alkoxyl-9-fluorenyl)serine acridine conjugate, which was achieved by a three-component assembly approach via an intramolecular reductive amination process.
引用
收藏
页码：129 / 135
页数：7
相关论文
共 50 条
  • [41] SYNTHESIS OF N-[AMIDINOBENZYL]-PHTHALIMIDES AND N-[AMIDINOPHENYL]-PHTHALIMIDES AND "N-[AMIDINOPHENYL]-1-OXOISOINDOLINES
    WAGNER, G
    WUNDERLICH, I
    PHARMAZIE, 1977, 32 (02): : 76 - 78
  • [42] A CONVENIENT SYNTHESIS OF N-(1-METHOXYALKYLIDENE) DERIVATIVES OF 6-AMINOPENICILLANIC AND 7-AMINOCEPHALOSPORANIC ACIDS
    MICETICH, RG
    SINGH, R
    SYNTHESIS-STUTTGART, 1985, (6-7): : 693 - 695
  • [43] GUINEA-PIG ILEITIS IS ATTENUATED BY THE LEUMEDIN N-(FLUORENYL-9-METHOXYCARBONYL)-LEUCINE (NPC-15199)
    MILLER, MJS
    CHOTINARUEMOL, S
    SADOWSKAKROWIKCA, H
    ZHANG, XJ
    MCINTYRE, JA
    CLARK, DA
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1993, 266 (01): : 468 - 472
  • [44] N-(fluorenyl-9-methoxycarbonyl)amino acid amide derivatives as a new class of anti-cancer agents
    Gera, L.
    Chan, D. C.
    Simkeviciene, V.
    Bunn, P. A.
    Stewart, J. M.
    BIOPOLYMERS, 2007, 88 (04) : 535 - 535
  • [45] NITROSO-SUBSTITUTED HETEROCYCLES - A CONVENIENT SYNTHESIS OF N-(2-PYRIDYL) RIBITYLAMINE AND N-(2-PYRIDYL)PYRROLES
    TAYLOR, EC
    RAMPAL, JB
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1983, 186 (AUG): : 253 - ORGN
  • [46] N-(Fluorenyl-9-methoxycarbonyl)amino Acid Amide Derivatives as a New Class of Anti-cancer Agents
    Gera, Lajos
    Chan, Daniel C.
    Simkeviciene, Vitalija
    Bunn, Paul A., Jr.
    Stewart, John M.
    PEPTIDES FOR YOUTH: THE PROCEEDINGS OF THE 20TH AMERICAN PEPTIDE SYMPOSIUM, 2009, 611 : 465 - 466
  • [47] Concurrent N- and C-Functionalization of Acridine with Ethyl Aryl-2-oxobut-3-ynoates in the Presence of Water: Synthesis of N-Alkenylacridin-9-ones
    L. P. Nikitina
    K. V. Belyaeva
    V. S. Gen’
    A. V. Afonin
    B. A. Trofimov
    Doklady Chemistry, 2022, 506 : 185 - 189
  • [48] Concurrent N- and C-Functionalization of Acridine with Ethyl Aryl-2-oxobut-3-ynoates in the Presence of Water: Synthesis of N-Alkenylacridin-9-ones
    Nikitina, L. P.
    Belyaeva, K. V.
    Gen', V. S.
    Afonin, A. V.
    Trofimov, B. A.
    DOKLADY CHEMISTRY, 2022, 506 (01) : 185 - 189
  • [49] Synthesis, characterization, and structures of 1-(9-fluorenyl)-germatrane and 1-(phenylacetylenyl)germatrane
    Zaitseva, GS
    Karlov, SS
    Churakov, AV
    Howard, JAK
    Avtomonov, EV
    Lorberth, J
    ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 1997, 623 (07): : 1144 - 1150
  • [50] Synthesis and properties of [Z]-2-(arylstannyl)-1-(9-hydroxy-9-fluorenyl) ethylene
    Qian, MX
    Fu, FX
    Pan, HD
    ACTA CHIMICA SINICA, 2000, 58 (01) : 105 - 111
12345