Adverse effects of antiretroviral therapy

被引：782
|
作者：
Carr, A [1 ]
Cooper, DA
机构：
[1] St Vincents Hosp, HIV Immunol & Infect Dis Clin Serv Unit, Sydney, NSW 2010, Australia
[2] Univ New S Wales, Natl Ctr HIV Epidemiol & Clin Res, Sydney, NSW, Australia
来源：
LANCET | 2000年 / 356卷 / 9239期
关键词：
D O I：
10.1016/S0140-6736(00)02854-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Antiretroviral toxicity is an increasingly important issue in the management of HIV infected patients. With the sustained major declines in opportunistic complications, HIV infection is a more chronic disease, and so more drugs are being used in more patients for longer periods. This review focuses on the pathogenesis, clinical features, and management of the principal toxicities of the 15 licensed antiretroviral drugs, including mitochondrial toxicity, hypersensitivity, and lipodystrophy, as well as more drug-specific adverse effects and special clinical settings.
引用
收藏
页码：1423 / 1430
页数：8
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