Neuromyelitis optica spectrum disorder is an inflammatory syndrome that is associated with many autoimmune conditions. We present the case of a patient who had longitudinally extensive transverse myelitis and antibodies to aquaporin 4 IgG (AQP4-IgG). Based on presence of lymphopenia, further workup revealed strong ANA positivity, anti-Sm antibodies, and low serum complements suggesting presence of systemic lupus erythematosus. The patient promptly responded to intravenous pulse methylprednisolone and five sessions of plasma exchange. At 1 year, she is on maintenance treatment with low dose prednisolone, azathioprine, and hydroxychloroquine, she has had no relapse and no other clinical features of lupus. This case is an illustration that neuromyelitis optica spectrum disorder can be the first manifestation of systemic lupus erythematosus.
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Cook Cty Hosp, Dept Internal Med, 1950 W Polk, Chicago, IL 60612 USACook Cty Hosp, Dept Internal Med, 1950 W Polk, Chicago, IL 60612 USA
Sami, Faria
Sami, Shahzad Ahmed
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Trinity Hlth Oakland Hosp, Dept Internal Med, 1950 W Polk, Chicago, IL 60612 USACook Cty Hosp, Dept Internal Med, 1950 W Polk, Chicago, IL 60612 USA
Sami, Shahzad Ahmed
Manadan, Augustine M.
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Rush Univ Med Ctr, Cook Cty Hosp, Rheumatol, Med Ctr, 1611 West Harrison St,Suite 510, Chicago, IL 60612 USACook Cty Hosp, Dept Internal Med, 1950 W Polk, Chicago, IL 60612 USA
Manadan, Augustine M.
Arora, Shilpa
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Rush Univ, Cook Cty Hosp, Rheumatol, Med Ctr, 1950 W Polk, Chicago, IL 60612 USACook Cty Hosp, Dept Internal Med, 1950 W Polk, Chicago, IL 60612 USA
机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Bonnet, F
Mercié, P
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CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, FranceCHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Mercié, P
Morlat, P
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Morlat, P
Hocke, C
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Hocke, C
Vergnes, C
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Vergnes, C
Ellie, E
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Ellie, E
Viallard, JF
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Viallard, JF
Faure, I
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Faure, I
Pellegrin, JL
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Pellegrin, JL
Beylot, J
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France
Beylot, J
Leng, B
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机构:CHU Bordeaux, Hop Haut Leveque, Ctr Francois Magendie,Clin Med Interne & Malad In, Serv Med Interne & Malad Infect, F-33604 Pessac, France