Neuromyelitis optica spectrum disorder and systemic lupus erythematosus

被引:5
|
作者
Thabah, M. M. [1 ]
Sekar, D. [1 ]
Pranov, R. [1 ]
Moulitej, M. M., V [1 ]
Ramesh, A. [2 ]
Kadhiravan, T. [1 ]
机构
[1] JIPMER, Dept Med, Pondicherry 605006, India
[2] JIPMER, Dept Radiodiag, Pondicherry, India
关键词
Lupus; NMOSD; LETM; plasmapheresis; myelitis; DEVICS-SYNDROME; AUTOANTIBODIES; MYELITIS;
D O I
10.1177/0961203319888692
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Neuromyelitis optica spectrum disorder is an inflammatory syndrome that is associated with many autoimmune conditions. We present the case of a patient who had longitudinally extensive transverse myelitis and antibodies to aquaporin 4 IgG (AQP4-IgG). Based on presence of lymphopenia, further workup revealed strong ANA positivity, anti-Sm antibodies, and low serum complements suggesting presence of systemic lupus erythematosus. The patient promptly responded to intravenous pulse methylprednisolone and five sessions of plasma exchange. At 1 year, she is on maintenance treatment with low dose prednisolone, azathioprine, and hydroxychloroquine, she has had no relapse and no other clinical features of lupus. This case is an illustration that neuromyelitis optica spectrum disorder can be the first manifestation of systemic lupus erythematosus.
引用
收藏
页码:1722 / 1726
页数:5
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