Expression and prognostic value of the standard CD44 protein in pulmonary adenocarcinoma

被引：0
|
作者：
Takanami, I [1 ]
Takeuchi, K [1 ]
Naruke, M [1 ]
机构：
[1] Teikyo Univ, Sch Med, Dept Surg 1, Itabashi Ku, Tokyo 173, Japan
来源：
ONCOLOGY REPORTS | 2000年 / 7卷 / 05期
关键词：
CD44S; prognostic indicator; pulmonary adenocarcinoma; tumor progression; metastasis;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We examined immunohistochemically the expression of the standard form of CD44 (CD44S) tissue specimens from 164 patients with pulmonary adenocarcinoma. Of the 164 specimens, 79 (48%) expressed CD33S and the incidence of expression correlated with the tumor size. The prognosis for CD44S positive patients was poorer than that of CD44S negative patients. Our findings suggest that CD44S plays an important role in tumor progression and that CD44S expression is a useful prognostic market for pulmonary adenocarcinomas.
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页码：1065 / 1067
页数：3
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