Chemoselective and diastereoselective synthesis of halogenated [1,3] oxazino [2,3-a] isoquinoline derivatives

被引：1
|
作者：
Asghari, Sakineh [1 ,2 ]
Habibi, Ahmad Khabbazi [1 ]
机构：
[1] Univ Mazandaran, Fac Chem, Dept Organ Chem, Babol Sar, Iran
[2] Univ Mazandaran, Nano & Biotechnol Res Grp, Babol Sar, Iran
来源：
HETEROATOM CHEMISTRY | 2017年 / 28卷 / 04期
关键词：
1,3] oxazino [2,3-a] isoquinoline; alpha-bromo ketone; alpha-chloro ketone; dimethyl acetylenedicarboxylate; isoquinoline; ONE-POT SYNTHESIS; QUINOLINE-DMAD ZWITTERION; EFFICIENT SYNTHESIS; 1,4-DIPOLAR CYCLOADDITION; 3-COMPONENT; HETEROCYCLES; SPIRO; ACETYLENEDICARBOXYLATES; ACETYLENES; CHEMISTRY;
D O I：
10.1002/hc.21378
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Chemoselective and diastereoselective synthesis of halogenated [1,3] oxazino [2,3-a] isoquinolines, based on one-pot three-component reactions of isoquinoline and dimethyl acetylenedicarboxylate in the presence of -chloro and -bromo ketone derivatives in good to high yields, are reported.
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页数：8
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