Chemoselective and diastereoselective synthesis of halogenated [1,3] oxazino [2,3-a] isoquinoline derivatives

被引：1

作者：

Asghari, Sakineh ^{[1
,2
]}

Habibi, Ahmad Khabbazi ^{[1
]}

机构：

[1] Univ Mazandaran, Fac Chem, Dept Organ Chem, Babol Sar, Iran

[2] Univ Mazandaran, Nano & Biotechnol Res Grp, Babol Sar, Iran

来源：

HETEROATOM CHEMISTRY | 2017年 / 28卷 / 04期

关键词：

1,3] oxazino [2,3-a] isoquinoline; alpha-bromo ketone; alpha-chloro ketone; dimethyl acetylenedicarboxylate; isoquinoline; ONE-POT SYNTHESIS; QUINOLINE-DMAD ZWITTERION; EFFICIENT SYNTHESIS; 1,4-DIPOLAR CYCLOADDITION; 3-COMPONENT; HETEROCYCLES; SPIRO; ACETYLENEDICARBOXYLATES; ACETYLENES; CHEMISTRY;

D O I：

10.1002/hc.21378

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chemoselective and diastereoselective synthesis of halogenated [1,3] oxazino [2,3-a] isoquinolines, based on one-pot three-component reactions of isoquinoline and dimethyl acetylenedicarboxylate in the presence of -chloro and -bromo ketone derivatives in good to high yields, are reported.

引用

页数：8

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