Molecular pathology of Alzheimer's disease

被引：1
|
作者：
Yamazaki, T [1 ]
Ihara, Y [1 ]
机构：
[1] Univ Tokyo, Fac Med, Dept Neuropathol, Bunkyo Ku, Tokyo 113, Japan
来源：
NEUROPATHOLOGY | 1997年 / 17卷 / 04期
关键词：
Alzheimer's disease; amyloid beta-protein; apolipoprotein E; presenilins;
D O I：
10.1111/j.1440-1789.1997.tb00051.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Recent molecular and cellular approaches to the nature of Alzheimer's disease (AD) have revealed that the disease has a heterogenous genetic background. Thus, AD is not a disease but a syndrome, In the present article we review the significance of the causative and susceptibility genes of AD identified to date and discuss future perspectives of AD research.
引用
收藏
页码：263 / 269
页数：7
相关论文
共 50 条
  • [31] Synaptic pathology in Alzheimer's disease
    Davidsson, P
    Blennow, K
    JOURNAL OF NEUROCHEMISTRY, 1996, 66 : S3 - S3
  • [32] Vascular pathology in Alzheimer's Disease
    Hulette, CM
    Ervin, JF
    Pannell, C
    Schmechel, DE
    Strittmatter, WJ
    Saunders, AM
    NEUROLOGY, 2001, 56 (08) : A182 - A182
  • [33] Dendritic Pathology in Alzheimer's Disease
    Baloyannis, S. J.
    PROCEEDINGS OF THE 6TH INTERNATIONAL CONGRESS ON THE IMPROVEMENT OF THE QUALITY OF LIFE ON DEMENTIA, PARKINSON'S DISEASE, EPILEPSY, MS AND MUSCOLAR DISORDERS, 2008, : 1 - 10
  • [34] The neurofibrillary pathology of Alzheimer's disease
    Goedert, M
    NEUROSCIENTIST, 1997, 3 (02): : 131 - 141
  • [35] Synaptic pathology in Alzheimer's disease
    Marie, H.
    JOURNAL OF NEUROCHEMISTRY, 2017, 142 : 35 - 35
  • [36] Cerebellar pathology in Alzheimer's disease
    Mavroudis, Ioannis
    HELLENIC JOURNAL OF NUCLEAR MEDICINE, 2019, 22 : 174 - 179
  • [37] Dendritic pathology in Alzheimer's disease
    Baloyannis, S. J.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2009, 283 (1-2) : 153 - 157
  • [38] Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease
    Kelly, Sarah C.
    He, Bin
    Perez, Sylvia E.
    Ginsberg, Stephen D.
    Mufson, Elliott J.
    Counts, Scott E.
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2017, 5 : 8
  • [39] Molecular understanding of aluminum bioinorganic chemistry in relevance to the pathology of Alzheimer's disease
    Anitha, S
    Shanmugavelu, P
    Gazula, VR
    Shankar, SK
    Menon, RB
    Rao, RV
    Rao, JKS
    Zecca, L
    GROUP 13 CHEMISTRY: FROM FUNDAMENTALS TO APPLICATIONS, 2002, 822 : 228 - 245
  • [40] Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease
    Sarah C. Kelly
    Bin He
    Sylvia E. Perez
    Stephen D. Ginsberg
    Elliott J. Mufson
    Scott E. Counts
    Acta Neuropathologica Communications, 5
12345