The Na+/Ca2+ exchange molecule -: An overview

被引:0
|
作者
Philipson, KD
Nicoll, DA
Ottolia, M
Quednau, BD
Reuter, H
John, S
Qiu, ZY
机构
[1] Univ Calif Los Angeles, Sch Med, Cardiovasc Res Lab, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Sch Med, Dept Physiol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Sch Med, Dept Med, Los Angeles, CA 90095 USA
关键词
Na+/Ca2+ exchange; NCX family; NCKX family; alpha repeat regions; CHX exchangers;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An overview of the molecular physiology of the Na+/Ca2+ exchanger is presented. This includes information on the variety of exchangers that have been described and their regulatory properties. Molecular insight is most detailed for the cardiac Na+/Ca2+ exchanger (NCX1). Parts of the NCS1 molecule involved in regulation and ion transport have been elucidated, and initial information on the topology and structure is available.
引用
收藏
页码:1 / 10
页数:10
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