Synthetic, structural and antimicrobial studies of some substituted 2,6-diphenyl-1-aza-7-oxa-4-spiro[2,5]octanes

被引:0
|
作者
Jambulingam, M [1 ]
Sathish, A [1 ]
Vasanthakumar, J [1 ]
Rakkiyappan, K [1 ]
机构
[1] PSG Coll Arts & Sci, Dept Chem, Coimbatore 641014, Tamil Nadu, India
关键词
synthesis; antimicrobial studies; spiro oxiranes; substituted 2,6-diphenyl-l-aza-7-oxa-4-spiro[2,5]octanes;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Different methyl substituted 2,6-diphenyl piperidones have been synthesized and subjected to the reaction with dimethyl sulphoxonium methyl ylide in the presence of potassium tertiary butoxide for the preparation of the corresponding spiro oxiranes. The structures of the products have been confirmed by various physical techniques.
引用
收藏
页码:1261 / 1268
页数:8
相关论文
共 50 条
  • [41] Synthesis, characterization and antimicrobial activities of 2-(5-substituted-3-phenyl-1H-indol-2-yl)-5-substituted-7H-[1, 3, 4] oxadiazolo/thiadiazolo[3, 2-a] [1, 3, 5] triazine-7-thiones
    Anekal, D. P., 1600, Journal of Chemical and Pharmaceutical Research, 3/668 Malviya Nagar, Jaipur, Rajasthan, India (05):
  • [42] Structure-antimicrobial activity relationship of 4- or 5-substituted 1-(2,6-Dichloro-4-trifluoromethylphenyl)-1H-1,2,3-triazole analogues
    Mohammad Sayed Alam
    Yoshihisa Ozoe
    Dong-Ung Lee
    Journal of the Korean Society for Applied Biological Chemistry, 2011, 54 : 149 - 153
  • [43] Structure-Antimicrobial Activity Relationship of 4-or 5-Substituted 1-(2,6-Dichloro-4-trifluoromethylphenyl)-1H-1,2,3-triazole Analogues
    Alam, Mohammad Sayed
    Ozoe, Yoshihisa
    Lee, Dong-Ung
    JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, 2011, 54 (01): : 149 - 153
  • [44] Synthesis, Characterisation and Antimicrobial Studies of some 2,6-bis(1,2,3-Triazol-4-yl)Pyridine Ruthenium(II) "Click" Complexes
    van Hilst, Quinn V. C.
    Vasdev, Roan A. S.
    Preston, Dan
    Findlay, James A.
    Scottwell, Synove O.
    Giles, Gregory I.
    Brooks, Heather J. L.
    Crowley, James D.
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 8 (04) : 496 - 505
  • [45] SYNTHETIC STUDIES IN DITERPENE SERIES .7. CYCLISATIONS OF 4,8-DIMETHYL-1-PHENYLNON-7-EN-4-OL AND 2,6-DIMETHYL-9-PHENYLNONA-2,6-DIENE AND THEIR MECHANISM
    NASIPURI, D
    BHATTACH.R
    GHOSH, CK
    JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1969, (05): : 782 - &
  • [46] NARCOTIC-ANTAGONISTS - SYNTHESIS AND EVALUATION OF SOME SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-1,4 - 2,6-DIMETHANO-3-BENZAZOCINES
    MONTZKA, TA
    MATISKELLA, JD
    JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (03) : 453 - 456
  • [47] Syntheses, Urease Inhibition, and Antimicrobial Studies of Some Chiral 3-Substituted-4-amino-5-thioxo-1H,4H-1,2,4-triazoles
    Akhtar, Tashfeen
    Hameed, Shahid
    Khan, Khalid Mohammed
    Choudhary, Muhammad Iqbal
    MEDICINAL CHEMISTRY, 2008, 4 (06) : 539 - 543
  • [48] Structural studies of some mesoionic 1,3-diphenyl-1,2,3,4-tetrazolium-5-aminides by nitrogen NMR techniques
    Jazwinski, J
    POLISH JOURNAL OF CHEMISTRY, 1999, 73 (10) : 1719 - 1724
  • [49] Synthesis of C2-symmetric 2,2′-bipyridines derived from 4-substituted 1,10,10-trimethyl-3-oxa-5-aza- tricyclo[5.2.1.02,6]decane
    Davies, SR
    Cain, CP
    Glossop, MT
    Mengent, ML
    Kee, TP
    SYNTHETIC COMMUNICATIONS, 2004, 34 (07) : 1191 - 1197
  • [50] Synthesis and antimicrobial activity of 8-substituted-7-fluoro-benzo[4,5] thiazolo [2,3-c][1,2,4] triazoles
    Hipparagi, S. M.
    Majunder, U. K.
    Nargund, L. V. G.
    Vinaykumar, R.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2007, 16 (04) : 401 - 402