Multifocal electroretinographic responses in sector retinitis pigmentosa

被引:3
|
作者
Giambene, Barbara [1 ]
Verdina, Tommaso [2 ]
Pennino, Monica [3 ]
Fabbrucci, Monica [3 ]
Cavallini, Gian Maria [2 ]
Menchini, Ugo [3 ]
机构
[1] Al Emadi Hosp, Doha, Qatar
[2] Univ Modena & Reggio Emilia, Inst Ophthalmol, Via Pozzo 71, I-41100 Modena, Italy
[3] Azienda Osped Univ Careggi, Ophthalmol Dept, Florence, Italy
关键词
Generalised retinitis pigmentosa; Multifocal electroretinography; Sector retinitis pigmentosa; RETINAL FUNCTION; RHODOPSIN; STANDARD; FIELD; ERG;
D O I
10.1007/s10792-019-01231-4
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Headings Multifocal electroretinography (mfERG) may be useful in the management of sector retinitis pigmentosa (SRP). Aim To compare multifocal electroretinographic responses in SRP, generalised retinitis pigmentosa (GRP), and healthy controls. Methods Eighteen patients with SRP, twelve with GRP, and fifteen controls were included in the study. All participants underwent: complete ophthalmological examination, Humphrey visual field testing, full-field ERG, and mfERG. The mean P1 amplitude, the implicit time (IT), and the mapping of the local responses were evaluated. Results The mean P1 amplitude was higher in the SRPs than in GRPs (p < 0.001), while it did not differ between SRPs and controls (p = 0.913). In the SRPs, the P1 amplitude in pathologic areas was higher than in the GRPs (p < 0.001). In normal areas, this parameter did not differ from the controls (p = 0.499). Moreover, in the SRPs, no differences in the P1 amplitude and the IT between pigmented and non-pigmented areas were found. Conclusion In the present study, the mfERG examination displayed significant differences between sector and generalised RP, showing normal values in sector RP even in pigmented areas. Considering the patients included in this study, SRP seems to represent a favourable variant of the disease, characterised by a limited retinal involvement and apparently mild functional damage. It is still unclear how these results can be extended to other forms of SRP.
引用
收藏
页码:703 / 708
页数:6
相关论文
共 50 条
  • [1] Multifocal electroretinographic responses in sector retinitis pigmentosa
    Barbara Giambene
    Tommaso Verdina
    Monica Pennino
    Monica Fabbrucci
    Gian Maria Cavallini
    Ugo Menchini
    International Ophthalmology, 2020, 40 : 703 - 708
  • [2] ELECTRORETINOGRAPHIC FINDINGS IN RETINITIS-PIGMENTOSA
    BERSON, EL
    JAPANESE JOURNAL OF OPHTHALMOLOGY, 1987, 31 (03) : 327 - 348
  • [3] FAMILIAL ELECTRORETINOGRAPHIC AND ADAPTOMETRIC STUDIES IN RETINITIS PIGMENTOSA
    GOODMAN, G
    GUNKEL, RD
    AMERICAN JOURNAL OF OPHTHALMOLOGY, 1958, 46 (03) : 142 - 178
  • [4] Multifocal electroretinography in retinitis pigmentosa
    Seeliger, M
    Kretschmann, U
    Apfelstedt-Sylla, E
    Rüther, K
    Zrenner, E
    AMERICAN JOURNAL OF OPHTHALMOLOGY, 1998, 125 (02) : 214 - 226
  • [5] SECTOR RETINITIS PIGMENTOSA
    KRILL, AE
    ARCHER, D
    MARTIN, D
    AMERICAN JOURNAL OF OPHTHALMOLOGY, 1970, 69 (06) : 977 - &
  • [6] Sector retinitis pigmentosa
    Palma-Carvajal, F.
    Salazar-Villegas, A.
    Ale-Chilet, A.
    Bernal-Morales, C.
    Dotti-Boada, M.
    Figueroa-Vercellino, J. P.
    Alforja, S.
    JOURNAL FRANCAIS D OPHTALMOLOGIE, 2020, 43 (02): : 186 - 188
  • [8] ELECTRORETINOGRAPHIC STUDIES OF FAMILIES WITH DOMINANT RETINITIS-PIGMENTOSA
    ANDREASSON, S
    ACTA OPHTHALMOLOGICA, 1991, 69 (02): : 162 - 168
  • [9] Multifocal electroretinography in segmental retinitis pigmentosa
    Palmowski, AM
    Allgayer, R
    Heinemann-Vernaleken, B
    Scherer, V
    Eich, W
    Ruprecht, KW
    OPHTHALMOLOGE, 2001, 98 (03): : 294 - 299
  • [10] CORRELATIONS BETWEEN PERIMETRIC AND ELECTRORETINOGRAPHIC MEASUREMENTS IN RETINITIS-PIGMENTOSA
    VINGOLO, EM
    IANNACCONE, A
    ONORI, P
    STEINDL, K
    RISPOLI, E
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1992, 33 (04) : 840 - 840