Signaling Bias and Antagonism of Pilocarpine for M3 Muscarinic Acetylcholine Receptor

被引:0
|
作者
Pronin, Alexey N.
Wang, Kelly
Slepak, Vladlen Z.
机构
来源
FASEB JOURNAL | 2018年 / 32卷 / 01期
基金
美国国家卫生研究院;
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
555.7
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Structural aspects of M3 muscarinic acetylcholine receptor dimer formation and activation
    Hu, Jianxin
    Thor, Doreen
    Zhou, Yaru
    Liu, Tong
    Wang, Yan
    McMillin, Sara M.
    Mistry, Rajendra
    Challiss, R. A. John
    Costanzi, Stefano
    Wess, Juergen
    FASEB JOURNAL, 2012, 26 (02): : 604 - 616
  • [32] Muscarinic acetylcholine receptor M3 in proliferation and perineural invasion of cholangiocarcinoma cells
    Feng, Yu-Jie
    Zhang, Bing-Yuan
    Yao, Ru-Yong
    Lu, Yun
    HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL, 2012, 11 (04) : 418 - 423
  • [33] Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor
    Floeser, Anja
    Becker, Katharina
    Kostenis, Evi
    Konig, Gabriele
    Krasel, Cornelius
    Kolb, Peter
    Buenemann, Moritz
    ELIFE, 2021, 10
  • [34] M1–M3 muscarinic acetylcholine receptor-deficient miceNovel phenotypes
    Dinesh Gautam
    Alokesh Duttaroy
    Yinghong Cui
    Sung-Jun Han
    Chuxia Deng
    Thomas Seeger
    Christian Alzheimer
    Jürgen Wess
    Journal of Molecular Neuroscience, 2006, 30 : 157 - 160
  • [35] Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation
    Yu, Huangfei
    Xia, Hongwei
    Tang, Qiulin
    Xu, Huanji
    Wei, Guoqing
    Chen, Ying
    Dai, Xinyu
    Gong, Qiyong
    Bi, Feng
    SCIENTIFIC REPORTS, 2017, 7
  • [36] Analysis of the promoter region of the gene for the human M3 muscarinic acetylcholine receptor.
    Puhl, HL
    Noti, JD
    Shay, T
    Mattison, J
    Aronstam, RS
    FASEB JOURNAL, 1996, 10 (03): : 2335 - 2335
  • [37] Overproduction of Human M3 Muscarinic Acetylcholine Receptor: An Approach Toward Structural Studies
    Romero-Fernandez, Wilber
    Garriga, Pere
    Borroto-Escuela, Dasiel O.
    BIOTECHNOLOGY PROGRESS, 2011, 27 (03) : 838 - 845
  • [38] Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists
    Liu, Hongtao
    Hofmann, Josefa
    Fish, Inbar
    Schaake, Benjamin
    Eitel, Katrin
    Bartuschat, Amelie
    Kaindl, Jonas
    Rampp, Hannelore
    Banerjee, Ashutosh
    Huebner, Harald
    Clark, Mary J.
    Vincent, Sandra G.
    Fisher, John T.
    Heinrich, Markus R.
    Hirata, Kunio
    Liu, Xiangyu
    Sunahara, Roger K.
    Shoichet, Brian K.
    Kobilka, Brian K.
    Gmeiner, Peter
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (47) : 12046 - 12050
  • [39] Pronounced conformational changes following agonist activation of the M3 muscarinic acetylcholine receptor
    Han, SJ
    Hamdan, FF
    Kim, SK
    Jacobson, KA
    Brichta, L
    Bloodworth, LM
    Li, JH
    Wess, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (26) : 24870 - 24879
  • [40] Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation
    Huangfei Yu
    Hongwei Xia
    Qiulin Tang
    Huanji Xu
    Guoqing Wei
    Ying Chen
    Xinyu Dai
    Qiyong Gong
    Feng Bi
    Scientific Reports, 7