Preparation of α-methylene-γ-butyrolactones with difluoromethylene functionalities

被引：0
|
作者：
Fukuda, H [1 ]
Kitazume, T [1 ]
机构：
[1] Tokyo Inst Technol, Dept Bioengn, Midori Ku, Yokohama, Kanagawa 226, Japan
来源：
HETEROCYCLES | 1997年 / 46卷
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4-(1,1-Difluoro-2-ethoxycarbonyl)methyl-gamma-butyrolactone (1) was prepared from the Reformatsky-type reaction of n-butyl 3-formylpropanoate with ethyl bromodifluoroacetate in Zn-THF system, and compound (1) was converted to alpha-methylene-gamma-butyrolactone derivatives with a difluoromethylene unit at gamma-position.
引用
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页码：275 / 285
页数：11
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