Animal models in peritoneal dialysis research: A need for consensus

被引：2
|
作者：
Mortier, S [1 ]
Lameire, NH [1 ]
De Vriese, AS [1 ]
机构：
[1] Ghent Univ Hosp, Renal Unit, B-9000 Ghent, Belgium
来源：
PERITONEAL DIALYSIS INTERNATIONAL | 2005年 / 25卷 / 01期
关键词：
animal models; biocompatibility;
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The development of an adequate animal model for peritoneal research remains an object of concern. In vivo peritoneal dialysis (PD) research is hampered by the large variety of available models that make interpretation of results and comparison of studies very difficult. Species and strain of experimental animals, method of peritoneal access, study duration, measures of solute transport and ultrafiltration, and sampling for histology differ substantially among the various research groups. A collective effort to discuss the shortcomings and merits of the different experimental models may Lead to a consensus on a standardized animal model of PD.
引用
收藏
页码：16 / 24
页数：9
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