2-((4-Phenyl-5-(2-(p-tolylamino)ethyl)-4H-1,2,4-triazol-3-yl)thio)-N′-(1-phenylethylidene)acetohydrazide

被引：2

作者：

Sermuksnyte, Aida ^{[1
]}

Jonuskiene, Ilona ^{[1
]}

Kantminiene, Kristina ^{[2
]}

Beresnevicius, Zigmuntas Jonas ^{[1
]}

Tumosiene, Ingrida ^{[1
]}

机构：

[1] Kaunas Univ Technol, Dept Organ Chem, Radvilenu Pl 19, LT-50254 Kaunas, Lithuania

[2] Kaunas Univ Technol, Dept Phys & Inorgan Chem, Radvilenu Pl 19, LT-50254 Kaunas, Lithuania

来源：

MOLBANK | 2022年 / 2022卷 / 02期

关键词：

1,2,4-triazole; hydrazone; Schiff base; antioxidative; ferric reducing antioxidant power (FRAP) assay; BIOLOGICAL EVALUATION; ANTIOXIDANT;

D O I：

10.3390/M1380

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of 2-((4-phenyl-5-(2-(p-tolylamino)ethyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide from 2-[(3-{2-[(4-methylphenyl)amino]ethyl}-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-yl)sulfanyl]acetohydrazide and acetophenone is reported. The title compound has been tested to possess 1.5-fold higher antioxidant ability than the control, butylated hydroxytoluene, as determined by a Ferric reducing antioxidant power assay.

引用

页数：5

共 50 条

[21] 4-(1H-1,2,4-Triazol-3-yl)-4H-1,2,4-triazole monohydrate
Jia, Li-Hui
Liu, Zu-Li
Liu, Wei
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O2766 - U1745
[22] The crystal structure of 4-(4-phenyl-5-(((1-(2,4,6-tribromophenyl)-1H-1,2,3-triazol-4-yl)methyl)thio)-4H-1,2,4-triazol-3-yl)pyridine, C22H14Br3N7S
Al-Sa'doni, Haitham
El-Naggar, Mohamed
Shehadi, Ihsan A.
Hasan, Kamrul
Khanfar, Monther A.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2024, 239 (06): : 1069 - 1072
[23] 2-{[5-(Adamantan-1-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N,N-dimethylethanamine
El-Emam, Ali A.
Lahsasni, Siham
Asiri, Hanadi H.
Quah, Ching Kheng
Fun, Hoong-Kun
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O1356 - +
[24] The 2-((4-Amino-5-((2,4-dichlorophenoxy)methyl)-4H-1,2,4-triazol-3-yl)thio)-1-(5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)ethan-1-one
Abdel-Wahab, Bakr F.
Mabied, Ahmed F.
Fettinger, James C.
Farahat, Abdelbasset A.
MOLBANK, 2023, 2023 (03)
[25] Synthesis, Crystal Structure and URAT1 Inhibitory Activity of 2-((5-Bromo-4-((4-cyclobutylnaphth-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio)acetic Acid
Zhang Xian-Sheng
Xin Xiao
Liu Wei
Xie Ya-Fei
Liu Chang-Ying
Wang Jian-Wu
Zhao Gui-Long
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2017, 36 (09) : 1425 - 1432
[26] Synthesis,Crystal Structure and URAT1 Inhibitory Activity of 2-((5-Bromo-4-((4-cyclobutylnaphth-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio)acetic Acid
张宪生
辛晓
刘巍
谢亚非
刘长鹰
王建武
赵桂龙
结构化学, 2017, 36 (09) : 1425 - 1432
[27] SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF 2-{[5-(2-CHLOROPHENYL)-4H-1,2,4-TRIAZOL-3-YL]SULFANYL}-1-(SUBSTITUTED PHENYL)ETHANONES
Karande, N. A.
Rathi, L. G.
PHARMACEUTICAL CHEMISTRY JOURNAL, 2017, 51 (07) : 558 - 563
[28] Synthesis and study of N-(1-phenylethylidene)-N-(4H-1,2,4-triazol-4-yl)amine, N'-(4H-1,2,4-triazol-4-yl)benzamidine, and cobalt(ii), nickel(ii), and copper(ii) complexes based on these ligands
Lider, E. V.
Peresypkina, E. V.
Volkova, K. A.
Abramova, E. V.
Shvedenkov, Yu. G.
Ikorskii, V. N.
Sheludyakova, L. A.
Smolentsev, A. I.
Lavrenova, L. G.
RUSSIAN CHEMICAL BULLETIN, 2008, 57 (09) : 1931 - 1943
[29] N-[(2-Phenyl-2H-1,2,3-triazol-4-yl)methylene]-2-(2-(2-phenyl-2H-1,2,3-triazol-4-yl)-3-{2-[(2-phenyl-2H-1,2,3-triazol-4-yl)methyleneamino]ethyl}imidazolidin-1-yl)ethanamine
Feng, Yue
Liu, Gang
Yue, Fan
Wang, Ji-De
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2008, 64 : O426 - O427
[30] Synthesis and characterization of some bi, tri and tetravalent transition metal complexes of N′-(furan-2-yl-methylene)-2-(p-tolylamino)acetohydrazide HL1 and N′-(thiophen-2-yl-methylene)-2-(p-tolylamino)acetohydrazide HL2
Emam, S. M.
AbouEl-Enein, S. A.
El-Saied, F. A.
Alshater, S. Y.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2012, 92 : 96 - 104

← 1 2 3 4 5 →