2-((4-Phenyl-5-(2-(p-tolylamino)ethyl)-4H-1,2,4-triazol-3-yl)thio)-N′-(1-phenylethylidene)acetohydrazide

被引:2
|
作者
Sermuksnyte, Aida [1 ]
Jonuskiene, Ilona [1 ]
Kantminiene, Kristina [2 ]
Beresnevicius, Zigmuntas Jonas [1 ]
Tumosiene, Ingrida [1 ]
机构
[1] Kaunas Univ Technol, Dept Organ Chem, Radvilenu Pl 19, LT-50254 Kaunas, Lithuania
[2] Kaunas Univ Technol, Dept Phys & Inorgan Chem, Radvilenu Pl 19, LT-50254 Kaunas, Lithuania
关键词
1,2,4-triazole; hydrazone; Schiff base; antioxidative; ferric reducing antioxidant power (FRAP) assay; BIOLOGICAL EVALUATION; ANTIOXIDANT;
D O I
10.3390/M1380
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A synthesis of 2-((4-phenyl-5-(2-(p-tolylamino)ethyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide from 2-[(3-{2-[(4-methylphenyl)amino]ethyl}-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-yl)sulfanyl]acetohydrazide and acetophenone is reported. The title compound has been tested to possess 1.5-fold higher antioxidant ability than the control, butylated hydroxytoluene, as determined by a Ferric reducing antioxidant power assay.
引用
收藏
页数:5
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