Allele frequencies of six miniSTR loci of three ethnic populations in Singapore

被引：11
|
作者：
Yong, R. Y. Y.
Gan, L. S. H.
Coble, M. D.
Yap, E. P. H.
机构：
[1] Def Med & Environm Res Inst, DSO Natl Labs, Singapore 117510, Singapore
[2] Natl Inst Stand & Technol, Div Biotechnol, Gaithersburg, MD 20899 USA
来源：
FORENSIC SCIENCE INTERNATIONAL | 2007年 / 166卷 / 2-3期
关键词：
MiniSTR; allele frequencies; population data; Singapore;
D O I：
10.1016/j.forsciint.2005.12.014
中图分类号：
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号：
0301 ; 10 ;
摘要：
MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR product sizes. This study investigated the allele frequency of six miniSTR loci, DIS1677, D2S441, D4S2364, DIOS1248, D14S1434 and D22S1045, in three Singapore populations. All loci showed a moderate degree of polymorphism with observed heterozygosity > 0.6 for all three populations. The allele frequencies, forensic parameters and heterozygosity comparison with other CODIS STR in similar populations are presented. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：240 / 243
页数：4
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