Restoring of wild-type activity level of high-fidelity SpyCas9 forms

被引：0
|
作者：
Karpov, D. [1 ]
Spasskaya, D. [1 ]
Davletshin, A. [1 ]
Garbuz, D. [1 ]
机构：
[1] Russian Acad Sci, Engelhardt Inst Mol Biol, Ctr Precis Genome Editing & Genet Technol Biomed, Moscow, Russia
来源：
FEBS OPEN BIO | 2021年 / 11卷
基金：
俄罗斯基础研究基金会;
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P-05.3-15
引用
收藏
页码：283 / 284
页数：2
相关论文
共 50 条
  • [31] High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice:: Synaptotoxicity without plaque formation
    Mucke, L
    Masliah, E
    Yu, GQ
    Mallory, M
    Rockenstein, EM
    Tatsuno, G
    Hu, K
    Kholodenko, D
    Johnson-Wood, K
    McConlogue, L
    JOURNAL OF NEUROSCIENCE, 2000, 20 (11): : 4050 - 4058
  • [32] High-Level Expression of Wild-Type p53 in Melanoma Cells is Frequently Associated with Inactivity in p53 Reporter Gene Assays
    Houben, Roland
    Hesbacher, Sonja
    Schmid, Corinna P.
    Kauczok, Claudia S.
    Flohr, Ulrike
    Haferkamp, Sebastian
    Mueller, Cornelia S. L.
    Schrama, David
    Wischhusen, Joerg
    Becker, Juergen C.
    PLOS ONE, 2011, 6 (07):
  • [33] High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays
    Schmid, C.
    Houben, R.
    Hesbacher, S.
    Kauczok, C. S.
    Flohr, U.
    Haferkamp, S.
    Mueller, C.
    Schrama, D.
    Wischhusen, J.
    Becker, J.
    JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2011, 9 (09): : 795 - 796
  • [34] HIGH-EFFICIENCY GENE-TRANSFER AND HIGH-LEVEL EXPRESSION OF WILD-TYPE P53 IN HUMAN LUNG-CANCER CELLS MEDIATED BY RECOMBINANT ADENOVIRUS
    ZHANG, WW
    FANG, XM
    MAZUR, W
    FRENCH, BA
    GEORGES, RN
    ROTH, JA
    CANCER GENE THERAPY, 1994, 1 (01) : 5 - 13
  • [35] HIGH-EFFICIENCY GENE-TRANSFER AND HIGH-LEVEL EXPRESSION OF WILD-TYPE P53 IN HUMAN LUNG-CANCER CELLS MEDIATED BY RECOMBINANT ADENOVIRUS
    ZHANG, WW
    FANG, XM
    MAZUR, W
    FRENCH, BA
    GEORGES, RN
    ROTH, JA
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1994, : 248 - 248
  • [36] Administering high-dose AAV9 vector in wild-type mice leads to complement activation, liver deposition, and concomitant liver-transaminase elevations
    Buchlis, G.
    Chorazeczewski, J.
    Ranken, C.
    Greig, J. A.
    Wilson, J. M.
    HUMAN GENE THERAPY, 2021, 32 (19-20) : A26 - A26
  • [37] Restoration of catalytic activity beyond wild-type level in glucoamylase from Aspergillus awamori by oxidation of the Glu400→Cys catalytic-base mutant to cysteinesulfinic acid
    Fierobe, HP
    Mirgorodskaya, E
    McGuire, KA
    Roepstorff, P
    Svensson, B
    Clarke, AJ
    BIOCHEMISTRY, 1998, 37 (11) : 3743 - 3752
  • [38] SUITABILITY OF ARABIDOPSIS FOR STUDIES ON INTRACELLULAR PH REGULATION - CORRELATION BETWEEN H+ PUMP ACTIVITY, CYTOSOLIC PH AND MALATE LEVEL IN WILD-TYPE AND IN A MUTANT PARTIALLY INSENSITIVE TO FUSICOCCIN
    BEFFAGNA, N
    ROMANI, G
    PLANT CELL AND ENVIRONMENT, 1994, 17 (06): : 681 - 690
  • [39] INTEGRATED HIGH-THROUGHPUT MIRNOMICS AND LIPIDOMICS ALLOW A DETAILED DISSECTION OF MIRNA TO MOLECULAR LIPID LEVELS CORRELATIONS IN WILD-TYPE, PCSK9 AND LDLR KNOCKOUT MICE
    Manzini, Stefano
    Busnelli, Marco
    Hilvo, Mika
    Chiara, Matteo
    Parolini, Cinzia
    Dellera, Federica
    Ganzetti, Giulia
    Horner, David
    Laaksonen, Reijo
    Chiesa, Giulia
    ATHEROSCLEROSIS, 2017, 263 : E35 - E35
  • [40] Lycopene supplementation inhibited high-fat diet-promoted hepatic tumorigenesis in both wild-type and beta-carotene-9′,10′-oxygenase knockout mice
    Blanche, I. P.
    Liu, Chun
    Smith, Donald
    von Lintig, Johannes
    Wang, Xiang-Dong
    FASEB JOURNAL, 2014, 28 (01):
12345