Component analysis of four-part extracts from Chamaecyparis obtusa Endl. by supercritical fluid extraction and anti-inflammatory effect on RAW 264.7cells

被引：7
|
作者：
Kwak, Byeong Mun [1 ]
Kim, Ee-Hwa [1 ]
Kim, Yong-Min [2 ]
Kim, Hee-Tack [3 ]
机构：
[1] Semyung Univ, Coll Korean Med, Dept Meridian & Acupoint, Jecheon, South Korea
[2] Semyung Univ, Dept Oriental Med & Herbal Cosmet Sci, Jecheon, South Korea
[3] Semyung Univ, Coll Korean Med, Dept Korean Med Ophthalmol & Otolaryngol & Dermat, 65 Semyeong Ro, Jecheon 27136, South Korea
来源：
JOURNAL OF EXERCISE REHABILITATION | 2019年 / 15卷 / 05期
关键词：
Chamaecyparis obtusa Endl; Supercritical fluid extraction; Anti-inflammatory effect;
D O I：
10.12965/jer.1938442.221
中图分类号：
R49 [康复医学];
学科分类号：
100215 ;
摘要：
The main purpose of this study was to suggest a solution for inflammation caused by urban daily fife based on supercritical extraction of Chamaecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Alpha-pinene, anti-inflammatory active compound of C. obtusa, was analyzed by electrospray ionization-mass spectrometry, gas chromatography, and gas chromatography mass spectrometry from each part of extracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtuse. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw material for natural product industry.
引用
收藏
页码：723 / 730
页数：8
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