Acute ischemic stroke: a rare complication of hump-nosed pit viper (Hypnale spp.) bite: a case report

被引:4
|
作者
Rathnayaka, R. M. M. K. Namal [1 ,2 ,3 ,6 ]
Ranathunga, P. E. A. Nishanthi [4 ]
Kularatne, S. A. M. [5 ]
Jayasinghe, Sanath [4 ]
机构
[1] Sabaragamuwa Univ Sri Lanka, Fac Med, Dept Pharmacol, Hidellana, Ratnapura, Sri Lanka
[2] Univ Peradeniya, Fac Vet Med & Anim Sci, Dept Vet Pathobiol, Peradeniya, Sri Lanka
[3] Teaching Hosp, Intens Care Unit, Ratnapura, Sri Lanka
[4] Teaching Hosp, Med Unit, Ratnapura, Sri Lanka
[5] Univ Peradeniya, Fac Med, Dept Med, Peradeniya, Sri Lanka
[6] 11 Flower Rd,New Town Housing Scheme 01, Ratnapura, Sri Lanka
关键词
Ischemic stroke; Hump-nosed pit viper; Hypnale; Snakebites; Sri Lanka;
D O I
10.1186/s13256-022-03442-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Hump-nosed pit viper is a medically important deadly venomous snake in Sri Lanka and is the commonest cause of venomous snakebites in the country. It frequently causes local effects and systemic manifestations such as acute kidney injury and coagulopathy that occur in less than 10% of all bites. This also includes some atypical presentations such as thrombotic microangiopathy and myocardial infarction. Currently, no antivenom is available for hump-nosed pit viper bites in Sri Lanka, and patients are managed with supportive treatment. This case illustrates an acute ischemic stroke following a hump-nosed viper bite, which is the second case in the literature. Case presentation A 71-year-old a Sinhalese male patient presented with left-sided hemiparesis with mouth deviation on day 2 of hump-nosed viper (Hypnale spp.) bite on the right foot. Non-contrast computed tomography of brain showed right ischemic stroke in internal capsule. He was given antiplatelets and statins and continued supportive treatment including limb physiotherapy and speech therapy. He recovered completely and was discharged on day 4 with clinic follow-up. Conclusions Physicians should be aware that ischemic cerebral infarcts may occur following hump-nosed pit viper bites.
引用
收藏
页数:5
相关论文
共 50 条
  • [21] Acute ischemic stroke following Hump-nosed viper envenoming; first authenticated case
    Vijayabala jeevagan
    Thashi Chang
    Christeine Ariaranee Gnanathasan
    Thrombosis Journal, 10 (1)
  • [22] Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: Antibody production with diagnostic and therapeutic potentials
    Tan, Choo Hock
    Tan, Nget Hong
    Sim, Si Mui
    Fung, Shin Yee
    Gnanathasan, Christeine Ariaranee
    ACTA TROPICA, 2012, 122 (03) : 267 - 275
  • [23] Hump-nosed pit viper (Hypnale hypnale) envenoming causes mild coagulopathy with incomplete clotting factor consumption
    Maduwage, K.
    Scorgie, F. E.
    Silva, A.
    Shahmy, S.
    Mohamed, F.
    Abeysinghe, C.
    Karunathilake, H.
    Lincz, L. F.
    Gnanathasan, C. A.
    Isbister, G. K.
    CLINICAL TOXICOLOGY, 2013, 51 (07) : 527 - 531
  • [24] Systemic bleeding including pulmonary haemorrhage following hump-nosed pit viper (Hypnale hypnale) envenoming: A case report from Sri Lanka
    Rathnayaka, R. M. M. K. Namal
    Ranathunga, P. E. A. Nishanthi
    Kularatne, S. A. M.
    TOXICON, 2019, 170 : 21 - 28
  • [25] Clinico-epidemiology of Hypnale zara (hump-nosed pit viper) envenoming in Sri Lanka
    Rathnayaka, R. M. M. K. Namal
    Ranathunga, P. E. A. Nishanthi
    Kularatne, S. A. M.
    TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2021, 115 (06) : 603 - 612
  • [26] Cross neutralization of Hypnale hypnale (hump-nosed pit viper) venom by polyvalent and monovalent Malayan pit viper antivenoms in vitro and in a rodent model
    Tan, Choo Hock
    Leong, Poh Kuan
    Fung, Shin Yee
    Sim, Si Mui
    Ponnudurai, Gnanajothy
    Ariaratnam, Christeine
    Khomvilai, Sumana
    Sitprija, Visith
    Tan, Nget Hong
    ACTA TROPICA, 2011, 117 (02) : 119 - 124
  • [27] Long-term health manifestations of hump-nosed pit viper (Genus: Hypnale) bites
    Rathnayaka, R. M. M. K. Namal
    Ranathunga, P. E. Anusha Nishanthi
    Kularatne, S. A. M.
    CLINICAL TOXICOLOGY, 2023, 61 (09) : 680 - 686
  • [28] First authenticated cases of life-threatening envenoming by the hump-nosed pit viper (Hypnale hypnale) in India
    Joseph, J. K.
    Simpson, I. D.
    Menon, N. C. S.
    Jose, M. P.
    Kulkarni, K. J.
    Raghavendra, G. B.
    Warrell, D. A.
    TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2007, 101 (01) : 85 - 90
  • [29] Epidemiology and clinical features of Hypnale nepa (hump-nosed pit viper) envenoming in Sri Lanka
    Rathnayaka, R. M. M. K. Namal
    Ranathunga, P. E. Anusha Nishanthi
    Kularatne, S. A. M.
    TOXICON, 2023, 231
  • [30] Nephrotoxicity of hump-nosed pit viper (Hypnale hypnale) venom in mice is preventable by the paraspecific Hemato polyvalent antivenom (HPA)
    Tan, Choo Hock
    Tan, Nget Hong
    Sim, Si Mui
    Fung, Shin Yee
    Jayalakshmi, Pailoor
    Gnanathasan, Christeine Ariaranee
    TOXICON, 2012, 60 (07) : 1259 - 1262