Breathprinting and Early Diagnosis of Lung Cancer

被引：44

作者：

Rocco, Gaetano ^{[1
]}

Pennazza, Giorgio ^{[2
]}

Santonico, Marco ^{[2
]}

Longo, Filippo ^{[3
]}

Rocco, Raffaele ^{[4
]}

Crucitti, Pierfilippo ^{[3
]}

Incalzi, Raffaele Antonelli ^{[5
]}

机构：

[1] Fdn Pascale, IRCCS, Ist Nazl Tumori, Div Thorac Surg,Thorac Dept, Naples, Italy

[2] Univ Campus Biomed, Dept Engn, Unit Elect Sensor Syst, Rome, Italy

[3] Univ Campus Biomed, Sect Thorac Surg, Rome, Italy

[4] Mayo Clin, Dept Surg, Div Thorac Surg, Rochester, MN USA

[5] Univ Campus Biomed, Div Geriatr Med, Rome, Italy

来源：

JOURNAL OF THORACIC ONCOLOGY | 2018年 / 13卷 / 07期

关键词：

Breathprint; Lung cancer; Biomarkers; Electronic nose; VOLATILE ORGANIC-COMPOUNDS; EXHALED BREATH ANALYSIS; CANINE SCENT DETECTION; CAMPUS BIO-MEDICO; PROOF-OF-CONCEPT; TERM FOLLOW-UP; ELECTRONIC-NOSE; MASS-SPECTROMETRY; CARBONYL-COMPOUNDS; PRINT ANALYSIS;

D O I：

10.1016/j.jtho.2018.02.026

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The electronic nose (e-nose) is a promising technology as a useful addition to the currently available modalities to achieve lung cancer diagnosis. The e-nose can assess the volatile organic compounds detected in the breath and derived from the cellular metabolism. Volatile organic compounds can be analyzed to identify the individual chemical elements as well as their pattern of expression to reproduce a sensorial combination similar to a fingerprint (breathprint). The e-nose can be used alone, mimicking the combinatorial selectivity of the human olfactory system, or as part of a multisensorial platform. This review analyzes the progress made by investigators interested in this technology as well as the perspectives for its future utilization. (C) 2018 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.

引用

页码：883 / 894

页数：12

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