Clinical trials: the viewpoint of children with a chronic illness compared with healthy children

被引:8
|
作者
Cherrill, J. [1 ]
Hudson, H.
Cocking, C.
Unsworth, V.
Franck, L. [2 ]
Fakis, A. [3 ]
McIntyre, J.
Choonara, I. [1 ]
机构
[1] Univ Nottingham, Div Child Hlth, Derbyshire Childrens Hosp, Acad Div Child Hlth,Med Sch, Derby DE22 3DT, England
[2] Great Ormond St Hosp Sick Children, Inst Child Hlth, London WC1N 3JH, England
[3] Derby City Gen Hosp, R&D Dept, Derby, England
关键词
UNDERSTAND;
D O I
10.1136/adc.2009.159145
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The views of over 200 children (11-16 years old, who were either healthy or attending paediatric medical clinics with a chronic illness) on issues relating to paediatric clinical trials were determined by a questionnaire. Children with a chronic illness had a better understanding of the concept of dosing of medicines (40% vs 23%) and placebo (34% vs 20%). They were more likely to support children's involvement in clinical trials (51% vs 37%). The altruistic nature of children in both groups was similar. It was of concern, however, that 57-63% children would participate as healthy volunteers in a cancer drug trial. Both groups were able to differentiate between the different types of illnesses where it is appropriate to study medicines in children (86-89% for illness where there is no treatment; 34-40% for 'me-too' drugs). Young people should be given more opportunities to be involved in decision-making regarding clinical trials of medicines.
引用
收藏
页码:229 / 232
页数:4
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