NICOTINAMIDE REJUVENATES EX-VIVO EXPANDED NATURAL KILLER CELLS AND ENHANCES THEIR TUMOR KILLING CAPACITY

被引:0
|
作者
Pato, Aviad [1 ]
Hailu, Astar [1 ]
Brickman, Nurit [1 ]
Yackoubov, Dima [1 ]
Cichocki, Frank [2 ]
Peled, Amnon [3 ]
Simantov, Ronit [1 ]
Lodie, Tracey [1 ]
Rifman, Julia [1 ]
Geffen, Yona [1 ]
Berhani-Zipori, Orit [1 ]
Edri, Avishay [1 ]
机构
[1] Gamida Cell, Jerusalem, Israel
[2] Univ Minnesota, Minneapolis, MN USA
[3] Hadassah Med Ctr, Jerusalem, Israel
关键词
D O I
10.1136/jitc-2021-SITC2021.162
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
162
引用
收藏
页码:A172 / A172
页数:1
相关论文
共 50 条
  • [21] Carfilzomib combined with ex vivo-expanded patient autologous natural killer cells for myeloma immunotherapy
    Chang, S. K.
    Hou, J.
    Chen, G. G.
    Yu, D. D.
    Wu, H. Q.
    Xie, Y. S.
    Hu, L. N.
    Gao, L.
    Xiao, W. Q.
    Kong, Y. Y.
    Tao, Y.
    Shi, J. M.
    NEOPLASMA, 2018, 65 (05) : 720 - 729
  • [22] An Uncoupling of Canonical Phenotypic Markers and Functional Potency of Ex Vivo-Expanded Natural Killer Cells
    Lieberman, Nicole A. P.
    DeGolier, Kole
    Haberthur, Kristen
    Chinn, Harrison
    Moyes, Kara W.
    Bouchlaka, Myriam N.
    Walker, Kirsti L.
    Capitini, Christian M.
    crane, Courtney A.
    FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [23] Efficacy of ex vivo activated and expanded natural killer cells and T lymphocytes for colorectal cancer patients
    Subramani, Baskar
    Pullai, Chithra Ramanathan
    Krishnan, Kohila
    Sugadan, Sheela Devi
    Deng, Xuewen
    Hiroshi, Terunuma
    Ratnavelu, Kananathan
    BIOMEDICAL REPORTS, 2014, 2 (04) : 505 - 508
  • [24] Evaluation of the reconstituting capacity of ex-vivo expanded hematopoietic stem and progenitor cells in a murine transplantation model.
    von Drygalski, A
    Alespeiti, G
    Ren, L
    Adamson, JW
    BLOOD, 1999, 94 (10) : 128A - 129A
  • [25] In-Vivo Persistence, Trafficking and Phenotypic Stability of Autologous, Ex-Vivo Expanded Rhesus Macaque Natural Regulatory T Cells
    Singh, K.
    Stempora, L.
    Garrett, A.
    Kirk, A.
    Larsen, C.
    Blazar, B.
    Kean, L.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2013, 13 : 77 - 77
  • [26] Ex-vivo expansion and mRNA transfection of cord blood derived natural killer cells with preserved cytotoxicity.
    Tuncer, Hande H.
    Betancur, Monica M.
    Boissel, Laurent H.
    Friedman, Robb S.
    Klingemann, Hans G.
    BLOOD, 2006, 108 (11) : 1045A - 1045A
  • [27] Synergistic cytotoxicity of ex vivo expanded natural killer cells in combination with monoclonal antibody drugs against cancer cells
    Deng, Xuewen
    Terunuma, Hiroshi
    Nieda, Mie
    Xiao, Weihua
    Nicol, Andrew
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2012, 14 (04) : 593 - 605
  • [28] A NOVEL CYTOKINE-ANTIBODY FUSION PROTEIN, N-820, TO ENHANCE THE FUNCTIONS OF EX-VIVO EXPANDED NATURAL KILLER CELLS AGAINST BURKITT LYMPHOMA
    Chu, Y.
    Nayyar, G.
    Su, N.
    Rosenblum, J.
    Soon-Shiong, P.
    Lee, J.
    Safrit, J.
    Barth, M.
    Lee, D.
    Cairo, M.
    LEUKEMIA RESEARCH, 2022, 121 : S17 - S18
  • [29] LARGE-SCALE EX-VIVO EXPANSION AND ACTIVATION OF HUMAN NATURAL-KILLER-CELLS FOR AUTOLOGOUS THERAPY
    MILLER, JS
    KLINGSPORN, S
    LUND, J
    PERRY, EH
    VERFAILLIE, C
    MCGLAVE, P
    BONE MARROW TRANSPLANTATION, 1994, 14 (04) : 555 - 562
  • [30] Epigenetic control of tumor cell killing by natural killer cells
    Pasion, Joyce
    Barisic, Darko
    Meydan, Cem
    Ng, Kong Y.
    Lafoz, Maria Tello
    Huse, Morgan
    Melnick, Ari
    Wendel, Hans-Guido
    CANCER RESEARCH, 2022, 82 (12)